Pediatr Crit Care Me
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Pediatr Crit Care Me · Nov 2021
Observational StudyFibrinolytic Impairment and Mortality in Pediatric Septic Shock: A Single-Center Prospective Observational Study.
Fibrinolytic shutdown is associated with poor prognosis in adult sepsis, but data in the pediatric population are sparse. This study aimed to identify the association between impaired fibrinolysis and mortality in pediatric septic shock. ⋯ Fibrinolytic shutdown in pediatric septic shock is associated with an increase in disease severity and mortality. This highlights the need for further investigations regarding whether fibrinolytic therapy improved the outcome of pediatric septic shock.