Pediatr Crit Care Me
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Delineation of multiple organ dysfunction syndrome (MODS) is important because of its frequent occurrence in the pediatric intensive care unit and its association with high mortality. However, studies in children are scarce, all have been done in developed countries, and, unlike adult studies, some showed that sepsis is not related to mortality. The aim of this study was to learn about the epidemiology of MODS in our pediatric intensive care unit and to observe if sepsis is associated with mortality. ⋯ MODS in children usually occurs early, and sepsis increases mortality. Hepatic and gastrointestinal failures are infrequent, and as has been suggested, they could be excluded from the majority of MODS diagnoses.
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Pediatr Crit Care Me · Apr 2003
Case ReportsDevelopment of bradycardia during sedation with dexmedetomidine in an infant concurrently receiving digoxin.
To describe the development of bradycardia during sedation with dexmedetomidine in a patient concurrently receiving digoxin. ⋯ This case adds to the limited data regarding dexmedetomidine in pediatric critical care and suggests that caution should be used when considering sedation with dexmedetomidine in patients also receiving digoxin.
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Pediatr Crit Care Me · Apr 2003
Correction factors for oxygen and flow-rate effects on neonatal Fleisch and Lilly pneumotachometers.
To assess the effects of different oxygen concentrations and flow rates on the measurement errors of neonatal pneumotachometers in heated and unheated situations and to develop correction factors to correct for these effects. ⋯ The effects of changes in oxygen concentrations and flow rates on neonatal pneumotachometers could be considerably decreased by the use of correction factors such as were calculated in this study. This will preclude frequent calibration procedures with actual flow and oxygen levels during changes in experimental settings.
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Pediatr Crit Care Me · Apr 2003
Case ReportsTreatment of acute lymphoblastic leukemia-induced extreme hypercalcemia with pamidronate and calcitonin.
To describe extreme hypercalcemia as the presenting feature of acute lymphoblastic leukemia in an 8-yr-old girl and the combined use of pamidronate and calcitonin for its treatment. ⋯ Extreme hypercalcemia can be a presenting feature of acute lymphoblastic leukemia, but it may not result in life-threatening organ dysfunction. Combined treatment with pamidronate and calcitonin should be considered for treating hypercalcemia that does not respond to conventional therapy with hydration and furosemide.