Mikrobiyol Bul
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It has been shown recently that signal-mediated interactions between the opportunistic pathogens Pseudomonas aeruginosa and Candida albicans affect virulence features in both organisms. It has been emphasized that the anti-candidal activity of P.aeruginosa is especially due to its pyocyanin pigment. The structure and the properties of monospecies biofilms and their role in infectious disease have been extensively studied. ⋯ In addition to the inhibitory effect of P.aeruginosa on Candida growth, in a dual species environment both organisms mutually suppressed each others' biofilm development quantitatively. These findings indicated that molecular basis of signal-mediated interaction between Pseudomonas and Candida spp. Should be clarified for better understanding of the pathogenesis of mixed bacterial-fungal infections.
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Chikungunya virus (CHIKV) is an arthropod-borne alphavirus that causes an acute febrile illness, chikungunya fever. CHIKV virus is geographically distributed in Africa, India, and South-East Asia. Chikungunya fever outbreaks have been reported from India since 2006. ⋯ This was the first laboratory confirmed imported Chikungunya case in Turkey. There are predictions regarding the presence of Aedes species mosquitos that can transmit this virus in Turkey. This case report will be an alarming signal for the clinicians in our country to consider Chikungunya fever in the differential diagnosis of patients presenting with fever, arthralgia and rash.
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The aim of this study was to investigate the tularemia seroprevalence among hunters mainly hunting in districts with emerging tularemia cases in Yozgat province located at the Central Anatolia region of Turkey. A total of 64 serum samples were collected from the subjects (all were male; age range: 18-67 years; mean age: 42.7 years) registered to Hunting and Shooting Clubs in Yozgat province and it's two districts, during January-April 2010 and anamnestic data were obtained using a questionnaire. The presence of Francisella tularensis antibodies in serum samples were screened by microagglutination test (MAT), and the positive samples were also confirmed by a commercial ELISA kit (Serazym, Germany). ⋯ The hunter with 1/2560 antibody titer developed acute oropharyngeal tularemia and treated with 14 days of ciprofloxacin therapy. Evaluation of risk factors in seropositive cases revealed consumption of spring water as a risk factor. In conclusion, our results indicated a considerable exposure of hunters to F.tularensis in Yozgat province and reflected a high prevalence of the pathogen around Yozgat, which coincided with the high notification rate of tularemia in this region.
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In this study, it was aimed to determine the frequency of the symptoms of influenza-like illness during influenza A (H1N1)v pandemic in two provinces where sentinel influenza surveillance was conducted and also to obtain opinions about H1N1 influenza and vaccination, H1N1 vaccination status and factors affecting vaccination. This cross-sectional study was conducted in the provinces of Ankara (capital city, located at Central Anatolia) and Diyarbakır (located at southeastern Anatolia). It was planned to include 455 houses in Ankara and 276 houses in Diyarbakır. ⋯ Those data emphasized the insufficient awareness of our population about the importance of pandemic influenza and vaccine. It is also believed that possible case definition in H1N1 case management scheme should be revised. In conclusion an important part of pandemic preparation plans is risk communication with the public to increase awareness and to prevent the missed opportunities.
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Tularemia is an infection caused by Francisella tularensis with a worldwide distribution and diverse clinical manifestations. In recent years, tularemia cases are increasing in Turkey, with a special attention to Marmara, western Blacksea and Central Anatolia regions. The aim of this study was to evaluate tularemia cases admitted to our hospital during an outbreak emerged at Central Anatolia between December 2009 and September 2010, making a point for the disease. ⋯ No severe complications were observed. The patients who applied to the hospital within 10 days of the initiation of the symptoms were treated successfully, while the others that applied later were not. In conclusion, tularemia which is an endemic disease in Turkey, should be kept in mind in patients with fever, sore throat and lymphadenopathy.