The Medical journal of Australia
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To examine inhospital mortality and morbidity associated with self-poisoning with different drug classes over an extended period. ⋯ Over two decades, there were decreases in poisonings by many highly toxic drugs which were associated with substantial reductions in morbidity and inhospital deaths. Despite massive increases in the number of antidepressant prescriptions, neither rates of self-harm nor the proportion of antidepressant poisonings increased markedly.