The Medical journal of Australia
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Two fatal cases of sporadic herpes simplex virus (HSV) encephalitis were seen and diagnosed at the Sir Charles Gairdner Hospital, Perth, between 1979 and 1981. Necropsy studies were directed to the possible portal of entry of HSV into the central nervous system. ⋯ No viruses were found in the Gasserian ganglia of either patient. The finding of HSV within an olfactory nerve provides further evidence of an olfactory portal of entry to the central nervous system in sporadic human HSV encephalitis.
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The present concepts of tropical eosinophilia are discussed on the basis of 50 cases observed in a service hospital, and with particular reference to earlier Indian studies. The importance of early diagnosis and therapy before irreversible damage develops is stressed. Further controlled studies in the aetiopathogenesis and clinical immunology are needed for better understanding of this continuing problem.