Medicinski arhiv
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Randomized Controlled Trial Comparative Study
Comparison of the motor and sensory block by ropivacaine and bupivacaine in combination with lidocaine in interscalene block.
The effects of ropivacaine and bupivacaine in interscalene block have been studied, but we usually combine lidocaine with ropivacaine or bupivacaine to fasten the onset. However, the effects of these combinations are not studied. ⋯ In interscalene block combined with lidocaine, ropivacaine had slower onset of motor block and longer duration of both blocks than bupivacaine. Only bupivacaine showed the different duration of the blocks between two concentrations.
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Inappropriate prescribing of a multiple therapeutic agents to patients with chronic conditions is very common in everyday practice. Adverse drug reactions (ADRs) are still considered as one of the main problems of drug therapy. We investigated idiosyncratic symptoms and signs of adverse drug reactions (ADRs) of the most frequent used combination of drugs among hospitalized patients prescribed polypharmacy. ⋯ The toxicity of some drug combinations may sometimes be synergistic and be greater than the sum of the risks of toxicity of either agent used alone. In order to recognize and to prevent ADRs (including drug interactions), good communication between pharmacist and patient and/or physicians and patient is crucial, and prescribers should develop an effective therapeutic partnership with the patient and with fellow health professionals.
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To assess the expression of psychosocial problems among children of parents with posttraumatic stress disorder (PTSD). ⋯ The results show that children of parents with PTSD express a significant behavioral problems, higher level of neurotism, internalisations, posttraumatic stress reactions, symptoms of intrusion and avoidance as well as significantly higher level of stress compared to children of parents without PTSD.
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The objective of this study was to validate an international instrument addressing family physicians' competency level from the primary health care sers' perspective in Albania, a post-communist country in Southeast Europe. ⋯ In the Albanian context, we provide evidence on the process of cross-cultural adaptation of a simple instrument measuring patients' self-perceived level of abilities and competencies of their family physicians regarding different domains of the quality of primary health care services.