Minerva medica
-
Review Meta Analysis
SNHG and UCA1 as prognostic molecular biomarkers in hepatocellular carcinoma: recent research and meta-analysis.
The latest studies have shown that the long non-coding RNAs seemed to be qualified markers of cancer. So we sought to assess the prognostic value of SNHG and UCA1 as predictive markers of patients with hepatocellular carcinoma (HCC). ⋯ Our meta-analysis demonstrated that SNHG and UCA1 may serve as prognostic biomarkers for HCC prognosis.
-
Small nucleolar RNA 47 promotes tumorigenesis by regulating EMT markers in hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is third leading cause of cancer-related death globally. Evidence suggest that small nucleolar RNAs (snoRNAs) have emerged as key regulators of tumor development and progression in HCC. However, the biological significance of snoRNAs in HCC remains unclear. ⋯ SnoRA47 may serve as a valuable biomarker and a potential therapeutic target for HCC.
-
Review Meta Analysis
Bisphosphonates use and risk of gastric cancer: an updated meta-analysis of cohort and case-control studies.
Studies evaluating the association between bisphosphonates exposure and gastric cancer (GC) risk have reached inconsistent conclusions. The purpose of this updated meta-analysis was to assess whether bisphosphonates exposure were associated with an increased risk of GC. ⋯ Our meta-analysis found no overall association between GC risk and bisphosphonates use. Further studies with large sample size and more covariate adjustments are needed.
-
Meta Analysis
Prognostic role of autophagy-related proteins in epithelial ovarian cancer: a meta-analysis of observational studies.
Autophagy has been reported to play important roles in tumorigenesis. This meta-analysis was conducted in order to investigate the association between autophagy-related proteins, beclin 1 and LC3, with prognostic value and clinical characteristics of ovarian cancer. ⋯ Autophagy-related proteins might be important markers of ovarian cancer progression. However, due to the limited number of original studies, more well-designed, large-scale, high-quality studies are needed, which provide new, valuable information for further investigation.