Minerva medica
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Review Meta Analysis
Long non-coding RNA H19 can predict a poor prognosis and lymph node metastasis: a meta-analysis in human cancer.
A long non-coding RNA (lncRNA) H19 has been reported to be aberrantly regulated in a wide range of cancers. This meta-analysis was performed to explore the potential value of H19 as a biomarker for cancer prognosis. ⋯ This meta-analysis showed that overexpression of H19 might potentially serve as a reliable biomarker for poor prognosis in different types of cancers.
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Review Meta Analysis
Long noncoding RNA ANRIL: a potential novel prognostic marker in cancer: a meta-analysis.
Numerous researches have showed that the dysregulation of lncRNA ANRIL play a significant role in cancer progression, and high expression of ANRIL may have important clinical value. This meta-analysis aims to investigate potential clinical application role of ANRIL as a biomarker for cancer prognosis. ⋯ High expression of ANRIL is associated with poor clinical outcome. ANRIL might be act as a novel potential prognostic biomarker in various cancers.
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Review Meta Analysis
Positive association between IL-16 rs1131445 polymorphism and cancer risk: a meta-analysis.
The association between IL-16 rs1131445 polymorphism and cancer risk is not consistent or even contradictory, this meta-analysis aims to investigate the role of IL-16 gene rs1131445 polymorphisms in the risk of cancer. ⋯ IL-16 rs1131445 C/T polymorphism is related to the susceptibility to cancer in Asians, suggesting that the C allelic gene of rs1131445 is significantly associated with an increasing cancer risk.
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Meta Analysis
The clinical risk factors associated with postoperative bile leakage after hepatectomy: a meta-analysis.
The occurrence of bile leakage (BL) is one of the major contributors to the morbidity after hepatectomy. However, the clinical risk factors associated with postoperative BL remains controversial. This study aims to further assess the risk factors for BL. ⋯ Our meta-analysis reveals that previous liver or biliary surgery, anatomic resection, major hepatectomy, right anterior sectionectomy, left trisectionectomy, central bisectionectomy, blood transfusion, operative time, bile duct reconstruction, resection of segments 1, 2 and 5 involved had significant positive correlation with increased risk of BL, on the contrary, hepatic fibrosis/cirrhosis, left lateral sectionectomy had the opposite effect.
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Meta Analysis
Meta-analysis of diagnostic value of serum Carbohydrate antigen 199 in pancreatic cancer.
Carbohydrate antigen 199 (CA199) has been used as a new promising serum biomarker for the diagnosis of pancreatic cancer. But its utility was full of controversies. This study sought to determine the diagnosis value of serum CA199 in pancreatic cancer through enrolling all the related eligible studies. ⋯ The current analyses indicated that CA199 is a valuable marker in the diagnosis of pancreatic cancer.