J Drugs Dermatol
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Case Reports
Case reports: minocycline-induced hyperpigmentation resolves during oral isotretinoin therapy.
Although disfiguring hyperpigmentation is a well-defined complication of minocycline therapy, modalities to reverse the phenomenon are unpredictable. We report a case of minocycline-induced, blue-black pigmentation in a 23-year-old Hispanic man, which resolved after treatment with oral isotretinoin for acne vulgaris.
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Topical anesthetic agents are frequently used by dermatologists to decrease the pain associated with a variety of cutaneous procedures, including laser surgery, soft tissue augmentation, and other cosmetic surgical treatments. These lidocaine-containing creams play an integral role in the cosmetic dermatology office by providing patient comfort with minimal side effects. This review of topical lidocaine preparations should aid practitioners in the selection of an appropriate topical anesthetic, taking into consideration its onset and duration of action and potential side effects.
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Lentigo maligna (LM) is an in situ melanoma that occurs in sun-damaged skin on the head and neck of elderly patients. Surgical excision is the treatment of choice for LM. However, surgical options may be limited by the location of LM in cosmetically sensitive areas. ⋯ Histologic clearance of the lentigo maligna was evident in skin biopsies. Imiquimod 5% cream appears effective in the treatment of lentigo maligna. We describe the treatment of a patient with facial LM with imiquimod 5% cream.
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Clinical Trial
Pilot study using topical imiquimod 5% cream in the treatment of nodular basal cell carcinoma after initial treatment with curettage.
Nodular basal cell carcinoma (nBCC) is the most common cutaneous malignancy and studies assessing the use of topical imiquimod 5% cream as a monotherapy in the treatment of nBCC have resulted in less than optimal clearance rates. ⋯ Imiquimod 5% cream appears to be an effective treatment method for nodular basal cell carcinoma if combined with curettage prior to application.
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Case Reports
Case reports: red scrotal syndrome: a localized phenotypical expression of erythromelalgia.
We report a case of red scrotal syndrome responding to oral gabapentin, a neuropathic mediator that is commonly used in the treatment of primary erythromelalgia. The positive response to oral gabapentin and the resemblance of these 2 conditions supports that red scrotal syndrome is a phenotypical expression of localized primary erythromelalgia.