Nederlands tijdschrift voor geneeskunde
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Lemierre's syndrome is a rare condition mostly secondary caused by an oropharyngeal infection with Fusobacterium necrophorum. We report a 62-year-old man with a classic case of Lemierre's syndrome, most likely caused by a diminished immunity as a result of an underlying chronic lymphatic leukemia.
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The first case report describes an extremely prolonged activated partial thromboplastin time (APTT) in a patient with no history of increased bleeding tendency. Heparin use was excluded. The APTT mixing study combined with the medical history suggests a deficiency in one of the non-essential coagulation factors. ⋯ Aberrations in the process of haemostasis can be efficiently screened using a platelet count, an APTT, a PT and a thorough physical examination combined with a thorough medical history taking. Common causes of prolonged PT and/or APTT are the use of oral anticoagulants or heparin, vitamin K deficiency and liver disease. Other causes include coagulation factor deficiencies, coagulation factor inhibitors and diffuse intravascular coagulation.
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Ketamine is used as an anaesthetic and in third-line pain management. Furthermore, recreational use of the drug is becoming increasingly popular due to its dissociative and hallucinogenic effects. Ketamine can affect the urothelium, possibly with long-term damage to the bladder and kidneys. ⋯ The precise mechanism of ketamine-associated urological symptoms is currently unknown. Treatment, therefore, is symptom-targeted and cessation of ketamine is imperative. We recommend that ketamine use is considered in patients with otherwise unexplained urological symptoms.
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Many medical doctors have become famous writers or poets. The two professions do have similarities: both have a professional preference for people in a crisis situation, both need to come close to their subject while maintaining a certain distance, the relationship between the individual and the general plays a central role in the practice of medicine and writing, writing and healing are similar in many ways and stories play an important role for both doctors and writers. We discuss these similarities in this article.
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Ned Tijdschr Geneeskd · Jan 2012
Case Reports[A woman with fever and a painful hip and lower back].
A 66-year-old woman presented with fever and acute pain in her lower back and left hip. She used prednison for arteritis temporalis. Abdominal radiography revealed no signs of free intraperitoneal gas, but instead a radiolucent area below the spleen suggesting free retroperitoneal gas. This was confirmed by CT-scan of the abdomen and surgery, when a diverticulitis of the colon descendens with retroperitoneal perforation was diagnosed.