Nederlands tijdschrift voor geneeskunde
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Ned Tijdschr Geneeskd · Jul 2006
Review Meta Analysis[Efficacy and adverse reactions of antipsychotics for neuropsychiatric symptoms in dementia: a systematic review].
To assess the efficacy and adverse reactions of typical and atypical antipsychotics in the treatment of neuropsychiatric symptoms in dementia, and to examine the evidence for the cerebrovascular events warning for atypical antipsychotics. ⋯ The efficacy of typical and atypical antipsychotics is comparable, but only low-dose risperidone seems to be associated with fewer (extrapyramidal) side effects. The adverse reactions are inadequately described in the published data and consequently the warning of an increased risk of mortality could not be confirmed.
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Ned Tijdschr Geneeskd · Jul 2000
Comment Meta Analysis[Acute low back pain: activity, NSAID's and muscle relaxants effective; bedrest and targeted exercise not effective; results of systematic reviews].
To inventory the current state of the art regarding the effectiveness of conservative treatment of acute low back pain. ⋯ Approximately two-thirds of the randomised trials in the field of back pain were of poor methodological quality. There was strong evidence that advice to stay active, non-steroidal anti-inflammatory drugs (NSAIDs) and muscle relaxants were effective in acute low back pain. There was also strong evidence that bed rest and specific exercises were not effective in acute low back pain. Strong evidence for effectiveness of many other commonly used interventions was lacking.
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Ned Tijdschr Geneeskd · Jul 2000
Meta Analysis[Chronic low back pain: exercise therapy, multidisciplinary programs, NSAID's, back schools and behavioral therapy effective; traction not effective; results of systematic reviews].
To inventory the current state of the art regarding the effectiveness of conservative treatment of chronic low back pain. ⋯ There was strong evidence that exercise therapy and multidisciplinary treatment programmes were effective in chronic low back pain, and moderate evidence that non-steroidal anti-inflammatory drugs (NSAIDs), back schools and behavioural therapy were effective in chronic low back pain. There was also strong evidence that traction was not effective in chronic low back pain. Strong evidence for effectiveness of many other commonly used interventions was lacking.
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In the Netherlands, the prevalence of overweight and obesity defined by Body Mass Indexes (BMI, weight in kg, divided by squared height in m) of 25-30 kg/m2 and > or = 30 kg/m2, respectively, is 30-40%. As to obesity, the prevalence of 7% in males and 11% in females is intermediate between the high prevalences in the USA and modernizing and industrializing developing countries and the low prevalences in China and Japan. However, the trend over the last decade is alarming. The Netherlands is amongst the highest together with the USA, UK and Germany; mainly males have an increased risk of obesity and youngsters and subjects with low education an increased risk of overweight.