Ann Acad Med Singap
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Ann Acad Med Singap · Mar 2000
Case ReportsSubcutaneous emphysema and pneumomediastinum after endotracheal anaesthesia.
We report a case of subcutaneous emphysema and pneumomediastinum that presented postoperatively after tracheal extubation. ⋯ We discussed the possible causes.
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Ann Acad Med Singap · Mar 2000
Comparative Study Clinical Trial Controlled Clinical TrialTotal intravenous anaesthesia using 3-in-1 mixture of propofol, alfentanil and mivacurium.
To avoid errors and confusion associated with 3 separate infusions, we conducted a feasibility study of total intravenous anaesthesia (TIVA) using 1 electrically-powered syringe pump to deliver a 3-in-1 mixture containing fixed proportions of propofol, alfentanil and mivacurium. ⋯ The 3-in-1 mixtures remained stable for up to 5 hours after preparation. It may be feasible to provide TIVA using the 3-in-1 mixture for induction and maintenance of anaesthesia in ASA 1 patients.
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Ann Acad Med Singap · Mar 2000
Case ReportsA case report of Aspergillus hypersensitivity syndrome with obstructing bronchial aspergillosis.
A 62-year-old Indian male with diabetes mellitus presented with atypical, overlap features of Aspergillus hypersensitivity syndrome and obstructing bronchial aspergillosis. ⋯ Culture and histologic examination of bronchoscopically identified tracheobronchial mucus plugs should be performed as early treatment may be life-saving.
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Ann Acad Med Singap · Jan 2000
Fibre-optic aided bougie (FAB) for simulated difficult tracheal intubation.
Difficult intubation remains a key problem and the value of the gum elastic bougie as a first approach is well recognised. ⋯ The fibre-optic assisted bougie (FAB) offers a promising technique in patients who may be difficult to intubate but who can be ventilated. Further developments are required to achieve a faster intubation time but oxygenation may be achieved by jetting down the hollow bougie.
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Ann Acad Med Singap · Jan 2000
Proerectile pharmacological effects of Tribulus terrestris extract on the rabbit corpus cavernosum.
The objective of the present study was to investigate the effect of oral treatment of Tribulus terrestris (TT) extract on the isolated corpus cavernosal tissue of New Zealand white (NZW) rabbits and to determine the mechanism by which protodioscin (PTN), a constituent of the TT, exerts its pharmacological effects. ⋯ The relaxant responses to acetylcholine, nitroglycerin and EFS by more than 10%, 24% and 10% respectively compared to their control values and the lack of such effect on the contractile response to noradrenaline and histamine indicate that PTN has a proerectile activity. The enhanced relaxant effect observed is probably due to increase in the release of nitric oxide from the endothelium and nitrergic nerve endings, which may account for its claims as an aphrodisiac. However, further study is needed to clarify the precise mechanism of its action.