Ann Acad Med Singap
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Ann Acad Med Singap · Sep 1992
Randomized Controlled Trial Clinical TrialAn assessment of preoxygenation techniques using the pulse oximeter.
The effect of preoxygenation with varying inspired oxygen concentration on the arterial oxygen saturation during induction of anaesthesia and intubation was studied using the pulse oximeter. Sixty-five healthy, young adults, (American Society of Anaesthesiologists Class I) undergoing elective surgery were randomly divided into three groups. Group I patients were not preoxygenated. ⋯ No patient had clinical signs of hypoxaemia. Patients who were preoxygenated with either 50% oxygen and nitrous oxide or 100% oxygen showed similar and clinically insignificant desaturation during this period. One minute after intubation and manual ventilation with 100% oxygen, the saturations of all patients returned to preinduction levels.
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Ann Acad Med Singap · May 1991
Randomized Controlled Trial Clinical TrialCetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study.
The efficacy of cetirizine dihydrochloride, a new H1-antagonist claimed to have minimal sedative property was evaluated in 28 patients with chronic idiopathic urticaria. Cetirizine 10 mg and placebo were compared in a double-blind cross-over trial. Response was measured by patients with daily charts on itch and wheals. ⋯ Five of the 28 (17.9%) patients reported mild drowsiness while taking cetirizine. Two patients reported drowsiness while on placebo. Tolerance was reported as good in 85%, moderate in 10% and bad in 5% according to patients' assessment, while tolerance was excellent and good in 80%, moderate in 15% of patients according to investigator's assessment.
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Ann Acad Med Singap · Jul 1986
Randomized Controlled Trial Clinical TrialA study of inhalational sedation with nitrous oxide/oxygen for oral surgery in Hong Kong Chinese.
Thirty healthy Chinese between 17-36 years undergoing extraction of bilaterally similarly impacted third molars in two visits were randomly given nitrous oxide/oxygen inhalational sedation to supplement local anaesthesia or unsupplemented local anaesthesia for operation on one side and the alternative for the other. The majority in the study had never heard of inhalational sedation being available to supplement local anaesthesia, and when given a chance to experience this method, the majority preferred it to local anaesthesia alone. ⋯ With both methods, the operating conditions were assessed to be good, with good patient co-operation. Inhalational sedation with nitrous oxide/oxygen had no significant effect on vital signs, intraoperative or post operative adverse effects and patients were street fit within ten minutes of ending sedation.
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Ann Acad Med Singap · Oct 1985
Randomized Controlled Trial Comparative Study Clinical TrialIs preoperative shaving really necessary?
A randomised prospective study was done to assess the necessity of shaving before operation. Seven hundred and sixteen cases were included in this study. ⋯ The clean wound infection rate was 5.08% for the traditional method group and 5.56% for the alternate method group. The results suggest that routine shaving, as part of preoperative preparation, has no advantage in reducing wound infection rate.