Arch Intern Med
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Randomized Controlled Trial Multicenter Study
Cognitive behavior therapy, exercise, or both for treating chronic widespread pain.
The clinical impact of telephone-delivered cognitive behavioral therapy (TCBT), exercise, or a combined intervention in primary care patients with chronic widespread pain (CWP) is unclear. ⋯ TCBT was associated with substantial, statistically significant, and sustained improvements in patient global assessment.
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Randomized Controlled Trial
Evaluation of a behavior support intervention for patients with poorly controlled diabetes.
Disease management programs that include ongoing telephone support for patients with diabetes have shown promise, but published studies have enrolled few socially and economically disadvantaged patients. ⋯ There was no significant effect of the experimental intervention compared with the control condition. The dose of intervention provided was less than in previously published studies. More intensive interventions may be necessary for the most disadvantaged patients.
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Randomized Controlled Trial
Nicotine therapy sampling to induce quit attempts among smokers unmotivated to quit: a randomized clinical trial.
Rates of smoking cessation have not changed in a decade, accentuating the need for novel approaches to prompt quit attempts. ⋯ Nicotine therapy sampling during a PQA represents a novel strategy to motivate smokers to make a quit attempt.
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Randomized Controlled Trial
Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms: a randomized, double-blind trial.
Concerns regarding the risk of estrogen replacement have resulted in a significant increase in the use of soy products by menopausal women who, despite the lack of evidence of the efficacy of such products, seek alternatives to menopausal hormone therapy. Our goal was to determine the efficacy of soy isoflavone tablets in preventing bone loss and menopausal symptoms. ⋯ In this population, the daily administration of tablets containing 200 mg of soy isoflavones for 2 years did not prevent bone loss or menopausal symptoms.
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Randomized Controlled Trial
Bupropion for smoking cessation in patients with acute coronary syndrome.
Smokers hospitalized with acute coronary syndrome (ACS) are at high risk for subsequent ischemic events. Nevertheless, over two-thirds of patients continue to smoke after an acute myocardial infarction. Bupropion hydrochloride has proven efficacy as a smoking cessation aid, but data regarding its safety and efficacy in ACS patients are limited. ⋯ In hospitalized patients with ACS who received continuous, intensive nurse counseling about smoking cessation, bupropion did not increase the rates of smoking abstinence.