Arch Med Sci
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In this study, we investigated the role of the long non-coding RNA GAPLINC in atherosclerosis under oxidized low-density lipoprotein (ox-LDL) treatment. ⋯ The present study demonstrates that upregulation of lncRNA GAPLINC represses the binding of miR-183-5p to the PDCD4 promoter region and then promotes PDCD4 expression, thereby inducing cell apoptosis and suppressing endothelial cell proliferation.
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Nutritional deficiencies remain a severe public health burden worldwide. They include some deficiencies and can lead to protein-energy malnutrition. Recent data has showed that inapprioprate nutrition and diet might be responsible for several milion deaths due to cardiovascular diseases. Thus, we aimed to determined the incidence rate of and DALYs due to nutritional deficiencies in 204 countries and territories. ⋯ From 1990 to 2019, the age-standardized incidence rate of and DALY rates due to nutritional deficiencies remained high in low-middle- and low-SDI areas, and Southeast Asia, Czechia, and Turkey had the highest levels of nutritional deficiencies.
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Influenza may be correlated with a high number of complications and generate high costs of treatment. The study aimed to estimate the socioeconomic significance of hospitalized influenza cases. ⋯ Influenza complications generate higher systemic and patient's costs, both direct and indirect. The group of children for whom the difference is especially marked is under 2 years of age.
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COVID-19 cases have rarely been reported in children. We sought to analyse the attack rate in paediatric population in Poland, focusing on local variations among the provinces, correlation with the number of tests per capita, and test positivity rate. ⋯ COVID-19 burden in children is significant. The local differences highlight various testing strategies, but the awareness of SARS-CoV-2 in children is essential. The correlation between attack rates in children and adults shows that the outbreak in children is parallel to the one observed in adults.
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This study aims to evaluate the predictive value of color Doppler ultrasound for the diagnosis of aberrant right subclavian artery (ARSA) with a co-occurring non-recurrent right laryngeal nerve (NRLN). ⋯ Aberrant right subclavian artery can be rapidly detected by ultrasonography. Aberrant right subclavian artery occurs when the RCCA originates from the aortic arch during detection. Patients with ARSA sometimes have co-occurring NRLN. Hence, vigilance in protecting the NRLN is needed during an operation.