Bratisl Med J
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to investigate the difference in serum tryptase levels between post-acute COVID-19 syndrome (PACS) patients and controls. ⋯ the role of mast cell activation in PACS remains unclear and further research is needed to fill the gaps in understanding the pathogenesis of this complex and heterogeneous disorder (Tab. 2, Ref. 17). Text in PDF www.elis.sk Keywords: post Acute COVID-19 syndrome, tryptase, mast cells, lactate dehydrogenase, ferritin.
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A pressing concern involves the efficient and intensive treatment of complications arising from malignant tumors in the hepatopancreatoduodenal region. This matter is closely tied to rectifying energy deficits, addressing insufficient body weight, and restoring proper metabolic processes. This is particularly crucial post-surgery, as the process is hindered by significant hypercatabolism, heightened nutritional requirements, and the presence of intoxication syndrome. ⋯ A notable degree of effectiveness in stabilizing and upholding the nutritional condition of patients was attainable within the isolated parenteral nutrition group. This achievement was realized by elevating the count of patients classified under "moderate" and "normal" nutritional statuses, and concurrently diminishing the number of patients experiencing severe and moderate nutritional insufficiency, respectively.The mixed type of nutritional support in this case can be considered with a high degree of probability as an alternative replacement for parenteral nutrition, due to the statically similar indicators of the nutritional status of patients achieved in this study (Fig. 4, Ref. 12).
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Prostate cancer is a significant health issue worldwide, with varying incidence and mortality rates across different regions. This study focuses on Slovakia, a country with an increasing trend in number of prostate cancer cases. The manuscript aims to provide a comprehensive overview of the burden of prostate cancer in Slovakia, encompassing epidemiological trends, economic impact, diagnostic approaches, and treatment modalities. The study emphasizes the need for effective management strategies and healthcare policies to address the increasing burden of this disease in the Slovak population. ⋯ The burden of prostate cancer in Slovakia is significant and growing, with rising incidence and economic costs posing challenges to the healthcare system. The study underscores the need for improved and early access to effective diagnostic and treatment options, and robust health policies to manage the rising burden. Additionally, public health initiatives focusing on awareness and early detection could play a crucial role in reducing the impact of prostate cancer in Slovakia. The findings of this study contribute valuable insights for policymakers and healthcare providers in developing targeted strategies to mitigate the burden of prostate cancer in the Slovak population (Tab. 7, Ref. 53).
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In patients with acute myeloid leukemia (AML), allogeneic hematopoietic stem cell transplantation (HSCT) remains the priority treatment option as the most effective prevention of relapse. When an HLA-matched sibling is available, these transplants are preferred. ⋯ The results presented in the work show the high efficiency of HSCT in each risk group. The number of induction therapies required to achieve CR is a good prognostic factor. The gender of a sibling has no impact on OS (Tab. 11, Fig. 7, Ref. 18). Text in PDF www.elis.sk Keywords: acute myeloid leukemia, allogeneic hematopoietic stem cell transplantation, overall survival, remission status, donor tender.
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Human papillomavirus is known to be the main cause of cervical cancer. Given that cervical cancer is still one of the leading causes of death in women of reproductive age, it is very important to prevent HPV infection and its persistence. ⋯ Various antioxidants have different abilities to influence the course of HPV-mediated cervical cancer. This study showed that women who did not consume fruits, and dark-green vegetables had a higher risk of HPV infection (Tab. 2, Fig. 3, Ref. 40): Text in PDF www.elis.sk Keywords: cervical cancer, human papillomavirus, folate, vitamin D3, dietary intake.