Bratisl Med J
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Randomized Controlled Trial Comparative Study
Comparison of a preincisional and postincisional small dose of ketamine for postoperative analgesia in children.
The aim of this randomized, double blind, placebo controlled prospective study was to investigate the preventive action of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine on postoperative analgesia by comparing its administration preincisionally, at the end of operation and placebo in the management of postoperative pain in children. ⋯ No significant difference was found between analgesic effects of preincisional ketamine, ketamine administered at the end of operation and of control group in postoperative analgesia in children (Tab. 1, Fig. 1, Ref. 21). Full Text (Free, PDF) www.bmj.sk.
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Randomized Controlled Trial
The use of controlled mild hypothermia and immune system status in patients with severe brain injury.
Severe brain injuries pose one of the most important problems on our health care because of their high morbidity and mortality. ⋯ Intensive treatment of intracranial hypertension fundamentally affects results of our treatment (Glasgow Outcome Score). The application of controlled mild hypothermia doesn't escalate the occurrence of extra cranial inflammatory complications after severe brain injury (Tab. 2, Fig. 11, Ref. 15).
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Randomized Controlled Trial
Correlation between the aPTT and clinical events in acute coronary syndromes treated with unfractionated heparin.
The primary objective of this study is to analyse relationship between activated partial thromboplastin time (aPTT) and clinical events in patients with unstable coronary artery disease. ⋯ The level of aPTT shows discordance with the onset of clinical events and is a weak predictor of outcomes (Tab. 2, Fig. 7, Ref 5).