Brit J Hosp Med
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The main role of early phase clinical trials in cancer is to determine the dose to take forward for future clinical study. However, study design is changing in order to account for the change in focus of drug development toward molecularly targeted agents.
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Leadership is a skill to be developed by all doctors from the foundation trainee to the director of the board. This article explores the impact of leadership style on performance and considers techniques to develop doctors' leadership skills and personal effectiveness.
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Soft tissue sarcomas are rare tumours which can be clinically difficult to differentiate from more common benign lesions. Imaging plays a fundamental role in diagnosis, but in some cases it can be difficult to differentiate benign from malignant conditions. This article reviews potential pitfalls in soft tissue sarcoma imaging.
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Emergency laparotomy is a common intra-abdominal procedure with outcomes recognized to be poor. Efforts are being made to improve these outcomes, both nationally and internationally. This article describes the methodology of a successfully implemented collaborative quality improvement project that improved outcomes following emergency laparotomy in four NHS trusts.