Brit J Hosp Med
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Severe sepsis affects large numbers of intensive care unit patients and is associated with high mortality rates. Understanding the epidemiology of sepsis is important to effectively allocate adequate resources. However, differences in definitions and in studied populations must be taken into consideration when interpreting and comparing the available epidemiological data.
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This article summarizes current knowledge about first trimester miscarriages from the clinician's perspective. The epidemiology of spontaneous miscarriage, its natural course and clinical findings are discussed together with the diagnostic management and therapeutic options, which include expectant, medical and surgical management.
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lisfranc injuries are fracture-dislocations of the torsometatarsal joint. They are usually associated with high energy trauma and are regularly overlooked. An early diagnosis and urgent orthopaedic referral is required to minimize the long-term consequences.