Cochrane Db Syst Rev
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Cochrane Db Syst Rev · Oct 2006
Review Meta AnalysisPreventing occupational stress in healthcare workers.
Healthcare workers can suffer from occupational stress which may lead to serious mental and physical health problems. ⋯ Limited evidence is available for the effectiveness of interventions to reduce stress levels in healthcare workers. Larger and better quality trials are needed.
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Cochrane Db Syst Rev · Oct 2006
Review Meta AnalysisAntithrombin for respiratory distress syndrome in preterm infants.
Acquired Antithrombin (AT) deficiency is a common and prognostically important finding in sick preterm infants with respiratory distress syndrome (RDS). It has been hypothesised that AT concentrate may improve clinical outcomes in preterm infants with RDS. ⋯ Preterm infants with RDS are unlikely to benefit from AT treatment and may be harmed.
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Cochrane Db Syst Rev · Oct 2006
Review Meta AnalysisAntibiotics for the prevention of acute and chronic suppurative otitis media in children.
Acute otitis media (AOM) is a common childhood illness. These middle ear infections may be frequent and painful. AOM may be associated with perforation of the tympanic membrane and can progress to chronic suppurative otitis media (CSOM). ⋯ For children at risk, antibiotics given once or twice daily will reduce the probability of AOM while the child is on treatment. Antibiotics will reduce the number of episodes of AOM per year from around three to around 1.5. We believe that larger absolute benefits are likely in high-risk children. These conclusions were not affected by sensitivity analyses.
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Cochrane Db Syst Rev · Oct 2006
Review Meta AnalysisNon-steroidal anti-inflammatory drugs for heavy bleeding or pain associated with intrauterine-device use.
Heavy bleeding and pain are the most common reasons why women discontinue IUDs. Non-steroidal anti-inflammatory drugs, which inhibit prostaglandin synthesis, have been shown to be effective in reducing menstrual bleeding and pain in women without IUDs. ⋯ Nonsteroidal anti-inflammatory drugs reduce bleeding and pain associated with IUD use. NSAIDs should be considered first-line therapy; if NSAIDs are ineffective, tranexamic acid may be considered as second-line therapy. Prophylactic ibuprofen administration with the first six menses after insertion appears unwarranted.
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Cochrane Db Syst Rev · Oct 2006
Review Meta AnalysisLaparoscopic versus open cholecystectomy for patients with symptomatic cholecystolithiasis.
Cholecystectomy is one of the most frequently performed operations. Open cholecystectomy has been the gold standard for over 100 years. Laparoscopic cholecystectomy was introduced in the 1980s. ⋯ No significant differences were observed in mortality, complications and operative time between laparoscopic and open cholecystectomy. Laparoscopic cholecystectomy is associated with a significantly shorter hospital stay and a quicker convalescence compared with the classical open cholecystectomy. These results confirm the existing preference for the laparoscopic cholecystectomy over open cholecystectomy.