Cochrane Db Syst Rev
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Cochrane Db Syst Rev · Jan 2000
ReviewNedocromil sodium for preventing exercise-induced bronchoconstriction.
Exercise-induced asthma causes cough, dyspnea, wheeze and chest tightness. Management of focuses on prevention through pharmaco-therapy and alternate strategies. Single use, pre-exercise beta2-agonists and non-steroidal anti-inflammatory agents such as the cromones are the most common treatments. ⋯ Nedocromil sodium used before exercise appears to reduce the severity and duration of exercise-induced bronchoconstriction. This effect appears to be more pronounced in people with severe exercise-induced bronchoconstriction.
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Amodiaquine has been widely used to treat malaria. Due to reports of fatal adverse drug reactions, discontinuation or modification of its use has been suggested. ⋯ There is some evidence to support the continued use of amodiaquine in the treatment of uncomplicated malaria, although drug resistance should be considered. Monitoring for toxicity should also continue.
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Cochrane Db Syst Rev · Jan 2000
ReviewGradual versus abrupt discontinuation of oxygen in preterm or low birth weight infants.
This section is under preparation and will be included in the next issue. ⋯ The results of this systematic review provide additional evidence linking routine exposure to high ambient oxygen in the early neonatal period to the development of ROP in preterm/LBW infants. However, due to small numbers and historical oxygen monitoring techniques, they provide little assistance to clinicians with regard to the most appropriate method of oxygen weaning, gradual or abrupt, in modern neonatal care settings.
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Cochrane Db Syst Rev · Jan 2000
ReviewEnergy/protein restriction for high weight-for-height or weight gain during pregnancy.
To assess the effects of prescribing a low-energy diet to pregnant women who are either overweight, or who exhibited high weight gain earlier in gestation, on subsequent weight gain, pre-eclampsia, and the outcome of pregnancy. ⋯ Protein/energy restriction of pregnant women who are overweight or exhibit high weight gain is unlikely to be beneficial and may be harmful to the developing fetus.
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Cochrane Db Syst Rev · Jan 2000
ReviewMaternal antigen avoidance during lactation for preventing atopic eczema in infants.
To assess the effects of prescribing an antigen avoidance diet to lactating mothers of infants with atopic eczema on the severity of the eczema. ⋯ The unimpressive results of this single trial should be interpreted with caution both because of its small size (n=17) and because the trial compared exposure to cow milk and egg with exposure to soya milk (soya can itself be allergenic). Maternal reports of changes in the severity of their breast-fed infants' eczema following ingestion of certain foods should be pursued by performing multiple (preferably double-blinded) challenges and dechallenges with the suspected foods.