Dtsch Arztebl Int
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Review
Exercise Training for Patients With Peripheral Arterial Occlusive Disease—Efficacy and Adherence.
One-third of all persons with peripheral arterial occlusive disease (PAOD) suffer from intermittent claudication. Exercise training under appropriate supervision is recommended in the pertinent guidelines, but physicians order it too rarely, and so-called vascular exercise groups are not available everywhere. This situation needs improvement in view of the impor - tance of walking ability and cardiorespiratory fitness for patients' quality of life and long-term disease outcome. ⋯ Exercise improves walking ability and lowers mortality. To attract patients with intermittent claudication to exercise training, a broad assortment of analog, digital and telemetric tools and a dense network of vascular exercise groups should be made available, along with regular contact between physicians and patients.
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Observational Study
Long-Term Trends in the Protection Against Severe Courses of COVID-19 by Vaccination—A Retrospective Observational Study in Older Persons During the Omicron Wave.
The long-term course of protection against severe COVID-19 courses by vaccine-induced or hybrid immunity in Germany is unclear. ⋯ These results indicate that, during the Omicron wave, the protection of older persons against a severe COVID-19 course gradually declined from six months after vaccination onward. The limitations of this study include confounders that could not be taken into account, possible misclassification of the cause of death, and selection bias due to missing information about vaccination status and severe COVID-19 courses.