Isr Med Assoc J
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Editorial Comment
Dialysis among the Treatment Options for Advanced Heart Failure.
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Multicenter Study
Serum Albumin Levels as a Predictor of Mortality in Patients with Sepsis: A Multicenter Study.
Low serum albumin is known to be associated with mortality in sepsis, as it reflects effects of nutrition, catabolism, and edema. ⋯ The decline in serum albumin one week after admission is a stronger predictor of mortality in younger patients. Older patients might have other reasons for low serum albumin, which reflect chronic co-morbidity rather than acuity of disease.
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Some studies have shown that patients who are hospitalized with severe COVID-19 also have low levels of vitamin D. It is known that vitamin D can reduce the risk of infections and down regulate the immune/inflammatory reaction. ⋯ This preliminary study confirms the high prevalence of vitamin D deficiency in patients with COVID-19 pneumonia and that vitamin D deficiency is associated with a reduction of lymphocyte subsets and altered T-lymphocyte activation. This finding may contribute to clarify the mechanisms by which vitamin D influences the course and outcome of COVID-19 pneumonia.