J Res Med Sci
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In this randomized, double-blinded study, we investigated the preemptive effects of propofol, remifentanil or ketamine on post-operative pain scores and analgesic requirements in elective lower abdominal surgeries under general anesthesia during the first 24 h of post-operative period. ⋯ Prophylactic preemptive single dose of intravenous (IV) 0.25 mg/kg propofol significantly decreased post-operative analgesia requirements comparing with IV 0.3 mg/kg ketamine or 0.25 μg/kg remifentanil.
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The purpose of this study is to determine sensitivity and specificity of body mass index (BMI) based on Center for Disease Control 2000 (CDC) percentiles compared to fat mass index (FMI) as an indicator of being really obese in children. Obesity was compared based on these two indexes among children under study. ⋯ Our results indicated 79% of children who were recognized as obese based on FMI, were also classified as obese according to BMI. Twenty-seven percent of children, who were non-obese, were identified as obese based on BMI. It appears that FMI compared to BMI is more accurate in determining obesity, but further studies are required.
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There is a broad variation in reported frequencies of seizure in multiple sclerosis (MS). In this study, the seizure and its characteristics analyzed among a large group of patients with MS. ⋯ Seizures can occur at any stage during the course of MS, but it is more common during the early stages.
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Reforms in inpatient care are critical for the enhancement of the efficiency of health systems. It still remains the main costly sector of the health system, accounting for more than 60% of all expenditures. Inappropriate and ineffective use of the hospital infrastructure is also a big issue. We aimed to analyze statistical data on health indices and dynamics of the hospital stock in Kazakhstan in comparison with those of developed countries. ⋯ The decreased level of beds may adversely affect both medical organization and health system operations. Alternatives to the existing inpatient care are now being explored. The introduction of the unified national healthcare system allows shifting the primary focus on primary care organizations, which can decrease the demand on inpatient care as a result of improving the health status of people at the primary care level.
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Anaplastic thyroid cancer (ATC) is a rare disease with an incidence of less than three cases per million of habitants in western countries. ATC accounts for 1-10% of all tumors derived from the thyroid gland. ⋯ Novel multitarget agents have shown promising responses; however, no positive randomized clinical trials are available up to now. To our knowledge, the case we are presenting here is the first reported case showing clinical and visual activity using sunitinib as a salvage treatment in an ATC patient who was not fit to receive systemic chemotherapy treatment.