Niger J Clin Pract
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We aimed to evaluate a comparative analysis of the prognostic value of the metastatic lymph node ratio (LNR) and pN (TNM) in stage III gastric cancer. ⋯ LNR was an independent significant prognostic factor and superior to pN staging in predicting OS but not for DFS in stage III gastric cancer patients. The high LNR levels in our research were found to be associated with poor survival rates. The percentile system we used to determine cutoff values may be considered as a reliable method. Similarly, LNR also provides a reliable prognostic parameter in future staging systems to help guide treatment algorithm plans.
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Cancer is one of the biggest health problems in the world. Colon adenocarcinoma is the third most common cancer and is the fourth most common cause of cancer deaths. The majority of colon adenocarcinomas originate from a previous adenoma. Cyclin D1 expression and Ki-67 proliferation index increase as the risk of malignancy transformation increases in adenomas. ⋯ In conclusion, immunohistochemical markers such as Cyclin D1 and Ki-67 will be helpful in differential diagnosis when there is difficulty in evaluating routine Hematoxylin-Eosin stained preparations between adenocarcinomas and adenomas.
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To assess the efficiency of ethylenediaminetetraacetic acid (EDTA), etidronic (HEBP), and peracetic (PAA) acids agitated with ultrasonic energy or diode laser on removing calcium hydroxide (CH) dressings from root canal walls. ⋯ Use of etidronic acid activated with ultrasonics or diode laser can be an appropriate irrigation regimen for CH removal from root canal system.
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To determine and compare the effects of different honey types on wound healing in an animal model, with silver sulfadiazine as the standard treatment. ⋯ The results of this study support the role of honey in wound healing, due to its antibacterial and immunomodulatory effects. More studies are needed to identify the role of honey composition in wound healing.
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The interest in risks related to inappropriate drug use (IDU) and polypharmacy among the elderly has increased in recent years. ⋯ IDU frequencies of the elderly patients are similar to the world literature in our study. As the number of chronic illnesses the patients had increases, the frequency of IDU increases according to Beers and STOPP criteria in our study.