Niger J Clin Pract
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Occupational lead (Pb) exposure causes multisystem effects at high and sustained low doses. However, there are inconsistencies in the dose-response effects on the thyroid and kidneys. ⋯ Though the mean levels of thyroid hormones and Cr were within their respective reference intervals, there was a preponderance of non-euthyroid status among participants in the present study with the majority of the participants falling within CKD grades 2 and 3.
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Case Reports
Etiologic dilemma and challenges of management of nodular vasculitis in tertiary health-care facility: A case report.
Nodular vasculitis is a rare inflammatory disease of the skin and subcutaneous fat tissue, characterized by crops of small, tender, erythematous nodules on the legs, mostly on the calves and shins. We present a 17-year-old adolescent female who presented with a six-month history of cough; recurrent fever and bilateral lower limb multiple ulcerated nodules of 1-month duration. ⋯ Histology of nodule biopsy revealed extensive caseous and coagulative fat necrosis, granulomatous inflammation with epitheloid macrophages and multinucleated giant cells surrounding the necrosis, and lymphoid infiltration of vessel walls with fibrous thickening of the intima, typical of Whitfield-type erythema induratum. There was initial but very transient response to antibiotic treatment, with further deterioration and eventual death from overwhelming sepsis.
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Case Reports
Non operative treatment of obturator dislocation with indentation fracture of the femoral head: A case report.
Traumatic anterior hip dislocation is quite rare and accounts for 7% to 15% of all hip dislocations. Approximately 70% of anterior hip dislocations are the obturator type and represent less than 7% of all hip dislocations. Indentation fracture of the femoral head complicates 35-55% of obturator dislocations. ⋯ Our index patient is a 19-year-old female who had conservative treatment for right obturator dislocation with indentation fracture of the femoral head. She recovered fully and had no features of osteonecrosis or secondary arthritis at 2 years postinjury. The aim of this report is to highlight the role of conservative treatment in the management of obturator dislocation with indentation fracture of femoral head.
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The oral cavity is colonized by a myriad of microorganisms, some of which are proven to be detrimental to human health. There have been numerous efforts to control the population of pathogenic agents in the oral cavity, including the usage of natural phytochemicals obtained from medicinal plants. Nasturtium officinale has long been used in traditional medicine for the management of hypertension, respiratory infections, and hyperglycemia, and its effectiveness against some microbes has been reported. ⋯ N. officinale extract effectively inhibited the growth of the tested oral bacteria at different concentrations but was more effective against S. mutans, E. faecalis, and S. aureus and so may be effective in managing some oral microbial infections.
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Dyke-Davidoff-Masson Syndrome (DDMS) is a rare clinical condition in which atrophy or hypoplasia of one cerebral hemisphere occurs secondary to brain insult during fetal or early childhood, which results in variable clinical manifestations like hemiparesis, seizures, expressive aphasia, and mental retardation. This rare entity mainly presents in childhood and is unusual in adults. DDMS is a rare cause of epilepsy and should be considered and excluded in cases of refractory seizures. ⋯ Magnetic resonance imaging (MRI) of the brain showed hyper-intensity in the right cerebral hemisphere, extensive atrophy of the right cerebral hemisphere involving the ipsilateral fronto-temporoparietal lobes, cerebral peduncle, and a contralateral megalencephaly, ipsilateral lateral ventricular dilatation, hypertrophic calvarium, hyperpneumatization of sphenoidal sinuses and midline shift due to loss of volume on the right. A diagnosis of Dyke-Davidoff-Masson syndrome was made; the patient did well on carbamazepine and physiotherapy. Caregivers were counseled, and the patient was discharged home and is currently on a follow-up visit.