Pak J Med Sci
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Objective of the study was to investigate effects of task specific circuit gait training to improve gait parameters and mobility among sub-acute and chronic stroke patients. A randomized control trial was conducted on stroke survivors of either gender being capable of standing 10 seconds and having 2-4 score on Rankin Modified Scale. Sample comprised of 30 participants randomly assigned into two groups. ⋯ After six weeks, significant improvement was recorded in TUG (p=0.014). Cadence (p=0.001), step length (p<0.001) and step width (p=0.009) were also significantly improved. Circuit gait training improves mobility and gait in stroke patients.
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Large spectrum of pathogenic BRCA mutations is known as a major cause of hereditary breast ovarian cancer in human all over the world. The objective of present study was to find out the association of mutations185-del-AG and 185Ins.A at BRCA1 exon-2 with age of onset and family history of gynecological cancer among the selected cohort of breast cancer patients in Pakistani population and to provide guidelines for treatment strategies. ⋯ BRCA1-185 Del AG mutation has association with early age onset of breast cancer. The direct sequencing is very useful approach for BRCA analysis and exon specific selected cohort from Pakistani population.
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To determine the frequency of an increase in intraocular pressure (IOP) after intravitreal triamcinolone acetonide (IVTA) in diabetic versus non-diabetic patients with various chorio-retinal disorders. ⋯ After IVTA, an IOP rise was observed more in diabetics than non-diabetic patients.
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To observe the changes and correlations of serum interleukins (ILs), adhesion molecules and soluble E-selectin (sE-selectin) in children with allergic rhinitis, asthma and both diseases. ⋯ Serum IL-4, IL-5, IL-10, adhesion molecules and sE-selectin are all involved in the pathogenesis of allergic rhinitis and asthma, which can be used to evaluate the degrees of respiratory allergic diseases.
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To explore the clinical effects upon gap nonunion of antibiotic-loaded bone cement spacer combined with membrane induction on infected bone defects. ⋯ The antibiotic-loaded cement spacer can control the local infection while maintaining the limb length and increasing the stability, reducing the contracture of bone and soft tissue, creating conditions for subsequent repair and reducing the infection rate of bone defects.