Pak J Med Sci
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To investigate the efficacy of acarbose combined with diet intervention in patients with primary polycystic ovarian syndrome (PCOS) complicated with impaired glucose tolerance (IGT) and its effect on their glycolipid metabolism. ⋯ The application of acarbose combined with diet intervention in patients with primary PCOS complicated with IGT can effectively enhance the efficacy, help patients increase ovulation rate and pregnancy rate, and improve sex hormone levels, glycolipid metabolism and inflammatory factor levels.
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Prisons are reported as hub for communicable disease, as the closed environment, overcrowding, poor hygienic conditions facilitate the disease transmission. This study was conducted to describe contact tracing to identify, educate and manage COVID-19 in camp jail Lahore and to describe clinical and epidemiological features of disease in prisoners. ⋯ In order to prevent Covid-19 outbreaks, proactive containment and comprehensive contact tracing to identify monitor and manage cases and contacts, in incarcerated facilities like prisons is a public health solution to prevent and control large scale epidemic. Active monitoring for infected patients, and implementing timely infection prevention and control measures are mandatory for highly infectious Covid-19 in this vulnerable population.
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Identification of colistin resistance and its bactericidal activity against gram-negative bacteria isolated from urinary tract infection (UTI) patients. ⋯ E.coli was the mainly responsible uropathogen causing UTIs. Colistin resistance was found in 22.8% gram negative uropathogens. Klebsiella pneumoniae isolates exhibited highest resistance to antibiotics.
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To analyze the immediate effect of platelet rich plasma, combined with celecoxib, on knee function and pain in patients with knee osteoarthritis. ⋯ Platelet rich plasma combined with celecoxib can promote the recovery of knee function and reduce pain in patients with knee osteoarthritis. This treatment combination also has a high immediate clinical effectiveness but needs further evaluation to find out the long term effects.
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Tuberculosis (TB) is a public health challenge and is endemic in many countries including Saudi Arabia. The disease is a major health concern in the Kingdom because of its dynamic population as resident expatriates are mainly from high TB burdened countries and the mass influx of pilgrims every year in peak seasons for Umrah and Hajj. The objective of the current study was to evaluate pulmonary TB incidence rates and conclude the potential high-risk patients to highlight the burdened regions in Saudi Arabia for the health authorities, which could help to establish policies of infection control as necessary. ⋯ TB control seems to be facing some challenges in several regions of the Kingdom, particularly major cities. National TB Control Program (NTP) needs to continually evaluate official data to spot high risk groups and factors associated with increased incidence. This will help to improve TB control strategies to contain the disease and approaches its eradication.