Pak J Med Sci
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To determine the efficacy of usage of topical autologous platelet rich fibrin (PRF) in improving outcomes of myringoplasty regarding graft uptake and hearing improvement. ⋯ Topical use of Platelet-Rich Fibrin during myringoplasty results in improved graft uptake. Hence, resulting in much improved hearing, significant reduction in infection rates and decrease in perforation sizes.
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Surgical patient mortality is progressively being measured for providing better management and care in different healthcare systems world-wide. The aim of this study was to assess mortality within a surgical department and to evaluate components associated with surgical and non- surgical deaths. ⋯ As per the study of three years (2015-2017) a fluctuating mortality pattern is observed. The increment of death was mainly among the unavoidable deaths such as GIT and Non GIT related sepsis, advanced malignancies, trauma and firearm injuries, pulmonary embolism myocardial infarction, a moderate role has also been played by miscellaneous group of patients. Delayed presentation of the patients after appearance of first symptom/ symptoms, delayed surgical decision/ exploration also came out to be significantly important factors in our studies elaborating the major difference in mortality rate.
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Case Reports
Spectral Domain - Optical Coherence Tomography findings in Triple-A Syndrome - A case series from Pakistan.
Triple A Syndrome is an autosomal recessive entity involving multiple systems usually characterized by adrenal insufficiency, alacrimia and achalasia. The disease features include variable degrees of neurological and neuro-ophthalmic manifestations. ⋯ Here we discuss a case series of five patients diagnosed as Triple A Syndrome. Clinically there was variable degree of optic atrophy in all the cases, which was further confirmed with spectral domain Optical Coherence Tomography The aim of this study was to publish the OCT based ONFL graphs of these unique cases, so that being an ophthalmologist we can take a multidisciplinary approach and decisions accordingly.
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To correlate the immunofluorescence (IF) findings on renal biopsies of patients of glomerulonephritis (GN) with the clinical course of the disease. ⋯ Immunofluorescence proved an important diagnostic tool in reaching the exact diagnosis in various types of GN. Distinct correlation between IF findings and clinical course of various types of GN was observed. IF negative cases had better outcome and was not having progressive course of disease so prognosis remained better than IF positive cases in this study.
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To describe the mode of presentation and frequency of external genital anomalies in disorder of sex development (DSD). ⋯ Disorders of sex development presented with a wide spectrum of external genital anomalies ranging from clitoromegaly in females to micropenis and hypospadias in males. There was also an extreme diversity in mode of presentation of these cases including pubertal delay, amenorrhea in females and gender confusion disorders.