Rev Invest Clin
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In recent decades, there has been an increase in the presence of metabolic disorders associated with obesity. Central in the treatment of these conditions, including abnormalities in glucose and lipid metabolism, dietary strategies play an important role. ⋯ The concept of personalized nutrition or precision nutrition has been recently developed, which states that diet is not the only factor accountable for metabolic responses such as postprandial glucose peaks, but that other factors are also involved, one of the most important of which is the gut microbiota. Therefore, the future of nutritional interventions is to generate algorithms based on the type of food consumed, biochemical parameters, physical activity, genetic variability, and especially the gut microbiota to predict the type of diet a person requires according to his or her metabolic alterations.
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The purpose of this perspective is to analyze the use of precision medicine and its potential for the next few decades with a special focus on the low- and middle-income countries, using diabetes as a paradigm. Precision medicine has improved the diagnosis, prevention, treatment, and prognosis of several malignant neoplasia. ⋯ Precision medicine has not fulfilled the expectations because it implies a long-term process composed by several feedback loops, and a number of internal and external validations and calibrations to target specific populations. If we want to obtain the expected benefits, the academic community and science agencies should work together to create the budgets and infrastructure that warrant the transfer of knowledge to the whole of society.
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I was the Editor-in-Chief of the Revista de Investigación Clínica (RIC) from December 1999-May 2014. In this article, I present a review about how I initiated my experience in the RIC as an author, how I became the Editor-in-Chief, the philosophy of the RIC during my time, the type of publications we had and the citations these papers have received today, the special issues and consensus we published and how the RIC became the official publication of the Mexican Institutes of Health.
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Since December 2019, when severe acute respiratory syndrome coronavirus 2 emerged in Wuhan, China, this virus and the resulting disease, coronavirus disease (COVID-19), has spread worldwide. What has occurred in this year and a half goes beyond anything we have dealt with, as humankind, in the past two centuries, perhaps obscured only by war. ⋯ Here, we aim to reflect on the basic structure of the virus and associate its behavior to that of determining factors of the human condition that may be modifiable soon. Needless to say, we find our effort clearly incomplete, and that both scientific and social aspects regarding COVID-19 or any other pandemic encountered in the future, will be constantly changing, from their beginning to their end.
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Historical Article
MY YEARS AS COEDITOR OF THE REVISTA DE INVESTIGACIóN CLíNICA AND THE 1993-1998 READERS OF OUR JOURNAL.
Some information on our readers during my years as coeditor of the Revista de Investigación Clínica are presented on the basis that readers, unlike editors, have no conflict of interest in evaluating scientific publications. The information provided is restricted to the past 6 years (1993-1998) of my 11 years as coeditor since the number of reader visits to our on-line articles began in 1993. ⋯ These figures suggest that our journal became at the end of the 20th Century a valuable information source for physicians in Mexico. It was the original idea that led Salvador Zubirán to launch this journal in 1948.