Saudi Med J
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To systematically review the literature to assess the quality of evidence related to corticotomy-assisted orthodontic treatment (CAOT) as adjunctive treatment in orthodontics. ⋯ Corticotomy-assisted orthodontic treatment should be considered with caution. Long term randomized clinical trials are still needed.
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To review cases of ovarian cysts managed at a University Hospital, and to identify the factors necessitating the use of laparotomy over laparoscopy. ⋯ Factors associated with laparotomy management rather than laparoscopy included older age more than 35, single, pregnant, or patients presenting with abdominal pain, and more than one cyst.
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Myocardial ischemia and reperfusion (I/R) injury is a pathological condition characterized by an initial restriction of blood supply to the heart followed by the subsequent restoration of perfusion and concomitant re-oxygenation. This condition may cause heart injury and contribute to morbidity and mortality. Although tremendous advances have been made in understanding the mechanisms of myocardial I/R injury, the translation of these findings into the clinical setting has been largely disappointing. ⋯ They are highly conserved and ubiquitously expressed in all species, which control diverse cellular functions by either promoting degradation or inhibiting target mRNA translation. In particular, a multitude of studies demonstrated miRNAs played an important role in acute and chronic cardiovascular disease processes. In this review, we focus on miRNAs and summarize the latest insights on the role of the specific miRNAs in myocardial I/R injury.
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Observational Study
The prevalence of thyroid cancer in patients with hyperthyroidism.
To determine the prevalence of thyroid cancer in patients with hyperthyroidism. ⋯ Many patients with hyperthyroidism in Muscat, Oman, especially those with Grave's disease, show malignancy, and hence a proper initial evaluation of these patients is required as part of long-term management.
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Mucormycosis is an uncommon acute invasive fungal infection that affects immunocompromised patients. It progresses rapidly and has poor prognosis if diagnosed late. Early detection, control of the underlying condition with aggressive surgical debridement, administration of systemic and local antifungal therapies, hyperbaric oxygen as adjunctive treatment improves prognosis and survivability.