Vojnosanit Pregl
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Randomized Controlled Trial Comparative Study Clinical Trial
[Cardiovascular effects of induction doses of the intravenous anesthetics, propofol, etomidate and thiopentone].
After reviewing the results of published comparative studies by numerous authors we have noticed that propofol, among the other intravenous anesthetics, has the strongest cardiovascular effects. The aim of this study was to compare the cardiovascular effects of induction doses of propofol, etomidate and thiopentone. A total of 165 female patients were randomly divided into three groups, and each one received a different anesthetic agent: propofol 2.5 mg/kg (n = 58), etomidate 0.3 mg/kg (n = 54) or thiopentone 5 mg/kg (n = 53). the patients were scheduled for abortion (gravidity up to 12 weeks of gestation) in out-patient conditions. ⋯ Following the administration of induction dose of propofol, a significantly greater decrease of systolic and diastolic blood pressure was observed then after the administration of etomidate or thiopentone. Slowing down of radial pulse was also more marked in propofol, then in etomidate or thiopentone group. The results of our study had shown that the induction dose of propofol had stronger effects on cardiovascular system, compared to the induction doses of etomidate or thiopentone.
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Randomized Controlled Trial Comparative Study Clinical Trial
[Propofol and thiopentone in elective cesarean section: effect on the mother and neonate].
All the anesthetics used for induction of anesthesia in cesarean section cross the placenta and can induce neonatal depression. The aim of this investigation was to compare intravenous anesthetics propofol and thiopentone as induction agents in patients scheduled for elective cesarean section and studying of their affection of mothers and new-born children. A total of 40 female patients were scheduled for elective cesarean section. ⋯ During the induction and maintenance of anesthesia, the frequency of adverse effects was greater in thiopentone, than in propofol group (6/20 versus 2/20 patients). There was no significant difference between the groups when induction-delivery (l-D) interval was concerned. The new-borns from the propofol group had significantly higher Apgar score in the 1st minute (8.35) and 5th minute (9.25), than the new-borns in thiopentone group (7.90 and 8.90, respectively).
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Randomized Controlled Trial Clinical Trial
[Premedication in peripheral block anesthesia].
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War injuries require specific approach in order to be optimally managed. In case of penetrating or explosive joint injuries, the management should be done with regard of the war surgery doctrine. Besides, it is very hard to prognose the disability degree after the completed treatment. ⋯ For all the reasons cited above, in the last two years we started with the total elbow arthroplasty. In all the patients with implanted elbow endoprosthesis, the improvement in the amplitude of elbow movements was observed. In 20% cases the pain was significantly decreased, and in 80% cases, the elbow became painless.