BMC anesthesiology
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Approximately 40 to 60% of patients with sepsis develop sepsis-induced cardiomyopathy (SIC), which is associated with a substantial increase in mortality. We have found that molecular hydrogen (H2) inhalation improved the survival rate and cardiac injury in septic mice. However, the mechanism remains unclear. This study aimed to explore the regulatory mechanism by which hydrogen modulates autophagy and its role in hydrogen protection of SIC. ⋯ Hydrogen exerts protective effect against SIC, which may be achieved through the promotion of autophagy and mitophagy.
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Retraction Of Publication
Retraction Note: Effect of apoptosis in neural stem cells treated with sevoflurane.