Anesthesia progress
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Anesthesia progress · Jan 2000
Randomized Controlled Trial Comparative Study Clinical TrialThe hypoalgesic effect of 3-D video glasses on cold pressor pain: reproducibility and importance of information.
The first aim of the study was to evaluate whether it was possible to manipulate the distraction effect induced by 3-D video glasses on the perceived pain and unpleasantness of the subjects by giving them different information about the expected effect. Second, the study aimed to determine the reproducibility of the effect. Forty-five students enrolled, 39 students participated in the study (24 women and 15 men, median age 23 years, range 19-28 years) because 6 did not show up for the first trial, and 37 completed the study because 2 subjects did not show up for the second trial. ⋯ The results of the pooled data showed a significant effect of 3-D video on perceived pain (P = .03) but not on unpleasantness (P = .18). After 4 weeks, the study was repeated, and there were no significant changes in the effect of video glasses. The median visual analogue scale scores were reduced in both the video and the control trials compared with the first session.
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Anesthesia progress · Jan 2000
Randomized Controlled Trial Clinical TrialOral transmucosal fentanyl pretreatment for outpatient general anesthesia.
The oral transmucosal formulation of fentanyl citrate (OTFC) has been reported to be an effective sedative, providing convenient and atraumatic sedation for children prior to general anesthesia or painful diagnostic procedures. Thirty-three young children (24-60 months of age) scheduled for outpatient general anesthesia for treatment of dental caries were enrolled in this randomized placebo-controlled clinical trial. To determine the effectiveness of the OTFC premedication, patient behavior was evaluated using three distinct outcome ratings. ⋯ The duration of surgery and the time of recovery did not differ between placebo and active premedication. Side effects including respiratory and cardiovascular complications were reported more frequently in the active fentanyl group. Continuous monitoring of respiratory function is essential when using this unique and effective formulation of fentanyl for pediatric preanesthetic sedation.
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Anesthesia progress · Jan 1999
Randomized Controlled Trial Comparative Study Clinical TrialUse of sevoflurane inhalation sedation for outpatient third molar surgery.
This study attempted to determine if sevoflurane in oxygen inhaled via a nasal hood as a sole sedative agent would provide an appropriate level of deep sedation for outpatient third molar surgery. Twenty-four patients scheduled for third molar removal were randomly assigned to receive either nasal hood inhalation sevoflurane or an intravenous deep sedation using midazolam and fentanyl followed by a propofol infusion. ⋯ A trend toward earlier recovery in the sevoflurane group was identified. Sevoflurane can be successfully employed as a deep sedative rather than a general anesthetic for extraction of third molars in healthy subjects.
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Anesthesia progress · Jan 1999
Randomized Controlled Trial Comparative Study Clinical TrialEvaluation of prilocaine for the reduction of pain associated with transmucosal anesthetic administration.
This investigation evaluated the use and efficacy of prilocaine HCl (4% plain Citanest) for minimizing pain associated with the intraoral administration of local anesthesia. Clinical anecdotes support the hypothesis that prilocaine without a vasoconstrictor reduces pain during injection. To determine relative injection discomfort, use of 4% plain prilocaine was compared with use of 2% lidocaine with 1:100,000 epinephrine and 2% mepivacaine with 1:20,000 levonordefrin. ⋯ However, there were statistically significant differences among the injection sites. Post hoc analysis revealed that prilocaine was associated with significantly less pain perception when compared to mepivacaine and lidocaine. These results suggest that differences in initial pain perception during transmucosal injection may be a function of the local anesthetic use, and prilocaine can produce less discomfort than the others tested.
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Anesthesia progress · Jan 1999
Randomized Controlled Trial Comparative Study Clinical TrialThe effect of a new type of video glasses on the perceived intensity of pain and unpleasantness evoked by a cold pressor test.
The aim of the study was to evaluate whether distraction induced by a new generation of video glasses (I-Glasses, Virtual i-O, Seattle, WA) has an effect on the perceived intensity of pain and unpleasantness. The effects of three-dimensional video, two-dimensional video, and no video glasses (control) were compared in two groups of healthy volunteers (13 males and 11 females) in a randomized, controlled trial. A cold pressor stimulus (1-2 degrees C chilled water) was used to induce experimental pain, and the volunteers rated the intensity of pain and unpleasantness on 100-mm visual analogue scales. ⋯ Three-dimensional video provided a significant reduction in both pain and unpleasantness (P < .01) compared with the control condition in the male group. However, in the female group, there was a significant reduction in unpleasantness with two-dimensional video compared with the control (P < .05). This suggests that the use of distraction by means of video glasses is able to reduce the perceived intensity of pain and unpleasantness.