Acta anaesthesiologica Belgica
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Acta Anaesthesiol Belg · Jan 1997
Randomized Controlled Trial Multicenter Study Clinical TrialSingle i.v. bolus dose of ondansetron in the prevention of postoperative nausea and emesis.
In this placebo controlled, double blind multicentre study, the efficacy and safety of a single i.v. bolus dose of ondansetron 4 mg were evaluated in the prevention of postoperative nausea and vomiting (PONV), which remains one of the most unpleasant side effects experienced by patients postoperatively. The study population included patients having general anesthesia and undergoing major gynecological or elective abdominal surgery by laparoscopy. ⋯ Several factors appeared to be associated with an increased risk of developing PONV, namely gender (female), type of surgery (gynecological), experience of previous PONV and duration of anesthesia; the use of propofol was not a significant factor. Ondansetron was well tolerated, with no side effect being reported as a significant problem.
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Acta Anaesthesiol Belg · Jan 1995
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialEfficacy and safety of oral tramadol and pentazocine for postoperative pain following prolapsed intervertebral disc repair.
In this multicenter double-blind randomized study the analgesic efficacy and safety of 50 mg tramadol was compared against 50 mg pentazocine by mouth in the treatment of 160 patients with acute pain following prolapsed intervertebral disc repair. The day of surgery patients were treated with parenteral opioids. The study started the morning after surgery. ⋯ Results showed both treatments provided equivalent effective analgesia for the six hours observation period. The global assessment of analgesia by patient and observer was not significantly different for both treatments, although less additional medication was required in the pentazocine group. Side effects were quite common in both groups, and occurred more frequently in the pentazocine group.
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Acta Anaesthesiol Belg · Jan 1995
Multicenter Study Comparative StudyPerformance of the anesthesiologists in 12 Departments of Anesthesia in Greece.
To assess the performance of anesthesiologists in 12 Departments of Anesthesia a questionnaire was completed by 132 anesthesiologists. The questionnaire included preoperative visit, preoxygenation, the anaesthetic record, time of stay in the operating room, management of apnea at the end of surgery and rapid sequence induction. Anesthesiologists were also asked if they keep update and how. ⋯ To induce anesthesia in patients with full stomach, 89% give thiopentone and succinylcholine, 4% thiopentone and nondepolarizing relaxant, 76% apply cricoid pressure and 5% inflate the lungs via a face mask, (P < 0.0001, P = 0.018 and P < 0.0001 respectively). Eighty-seven percent of the anesthesiologists keep update attending congresses, 76% departmental meetings (P = 0.0015 within the 12 Hospitals), 86% reading journals and 78% reading textbooks. The 12 Departments of Anesthesia presented a uniformity in updating knowledge but not in practicing anesthesia.