Middle East journal of anaesthesiology
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Middle East J Anaesthesiol · Feb 2013
Review Meta AnalysisAnalgesic efficacy of continuous intravenous magnesium infusion as an adjuvant to morphine for postoperative analgesia: a systematic review and meta-analysis.
The efficacy of perioperative intravenous magnesium administration on postoperative opioid use, opioid-related side effects (e.g., nausea and vomiting) and pain are uncertain, as randomized controlled trials on this topic have reported disparate results. The objective of this systematic review is to determine if perioperative magnesium reduces opioid use, opioid-related side effects, and postoperative pain. ⋯ Based on the results of this systematic review, perioperative intravenous magnesium may be a useful adjuvant for the management of postoperative pain providing analgesia through a different mechanism of action than that of opioids and would make a potential addition to a multimodal anlgesic treatment plan; however, the decrease in opioid use with perioperative magnesium infusion does not appear to be associated with a decresea in opioid-related side effects.
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Middle East J Anaesthesiol · Feb 2013
Randomized Controlled Trial Comparative StudyA comparative study of post operative analgesia, side effects profile and patient satisfaction using intrathecal fentanyl with and without morphine 0.1 mg in caesarean section.
This was a double-blinded, prospective randomized controlled trial to compare the postoperative analgesia, side effects profile and overall satisfaction in patients who received intrathecal fentanyl with or without morphine for elective Caesarean. ⋯ There was significant difference in terms of lower pain score, higher incidence of side effects with better patients' overall satisfaction in morphine group.
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Middle East J Anaesthesiol · Feb 2013
Randomized Controlled TrialScalp nerve blockade reduces pain after headframe placement in radiosurgery: a double blind, randomized clinical trial.
Patients undergoing stereotactic headframe placement for radiosurgery report that discomfort associated with the headframe often lasts for the duration of the treatment day (approximately 6 hours). We hypothesize that blockade of scalp nerves prior to headframe placement reduces the incidence of moderate to severe head pain during the entire treatment day. We describe a randomized, double-blind, placebo-controlled study of awake patients having radiosurgery for intracranial pathology that examines whether scalp nerve blockade and local anesthetic infiltration results in superior patient comfort versus infiltration alone. ⋯ Scalp nerve block significantly decreased moderate to severe head pain in radiosurgery patients throughout the treatment day.
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Middle East J Anaesthesiol · Feb 2013
Randomized Controlled Trial Comparative StudyA comparison of rectal misoprostol and intravenous oxytocin on hemorrhage and homeostatic changes during cesarean section.
Post partum bleeding is a major cause of mortality and morbidity in pregnant women. In this study the effects of rectal misoprostol and oxytocin on post-cesarean bleeding are compared. ⋯ Misoprostol is an appropriate alternative for intravenous oxytocin in patients undergoing cesarean section, with lesser side effects and longer duration of action.