World journal of gastroenterology : WJG
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World J. Gastroenterol. · Apr 2013
Randomized Controlled Trial Comparative StudyEffects of different resuscitation fluid on severe acute pancreatitis.
To compare effects of different resuscitation fluid on microcirculation, inflammation, intestinal barrier and clinical results in severe acute pancreatitis (SAP). ⋯ Results indicated that combination of normal saline, HES and glutamine are more efficient in resuscitation of SAP by relieving inflammation and sustaining the intestinal barrier.
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World J. Gastroenterol. · Mar 2013
Routine defunctioning stoma after chemoradiation and total mesorectal excision: a single-surgeon experience.
To investigate the 10-year results of treating low rectal cancer by a single surgeon in one institution. ⋯ Neoadjuvant CRT followed by TME, combined with routine defunctioning stoma construction and high-volume surgeon experience, can provide excellent surgical quality and good local disease control.
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World J. Gastroenterol. · Mar 2013
Value of α-fetoprotein in association with clinicopathological features of hepatocellular carcinoma.
To explore the relationship between α-fetoprotein (AFP) and various clinicopathological variables and different staging system of hepatocellular carcinoma (HCC) thoroughly. ⋯ HCC differentiation, size and vascular invasion have strong relationships with AFP, poor differentiation and HCC size ≥ 10 cm are independent predictors of elevated AFP. BCLC shows better relationship with AFP.
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World J. Gastroenterol. · Mar 2013
Comparative StudyRates and impact of hepatitis on human immunodeficiency virus infection in a large African cohort.
To determine the rates and impact of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections on response to long-term highly active antiretroviral therapy (HAART) in a large human immunodeficiency virus (HIV) population in Nigeria. ⋯ High rates of HBV and HCV infections were found in this HIV cohort. CD4 recovery was significantly diminished in patients with HBV co-infection.
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World J. Gastroenterol. · Mar 2013
Scolopendra subspinipes mutilans protected the cerulein-induced acute pancreatitis by inhibiting high-mobility group box protein-1.
To evaluate the inhibitory effects of Scolopendra subspinipes mutilans (SSM) on cerulein-induced acute pancreatitis (AP) in a mouse model. ⋯ These results suggest that SSM plays a protective role during the development of AP and pancreatitis associated lung injury via deactivating c-Jun NH2-terminal kinase, p38 and NF-κB.