Zhonghua wei zhong bing ji jiu yi xue
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Mar 2013
[The influence of pre-B-cell colony enhancing factor on adhesive molecule in pulmonary cells in rats with acute lung injury/acute respiratory distress syndrome].
To observe the influence of pre-B-cell colony enhancing factor (PBEF) on intercellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in lung tissue of rats with acute lung injury/acute respiratory distress syndrome (ALI/ARDS) induced by oleic acid. ⋯ PBEF could aggravate migration of pro-inflammatory cells to infiltrate the lung tissue by increasing the expression of ICAM-1 and VCAM-1, thus it plays an important role in the development of ALI/ARDS.
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Zhonghua Wei Zhong Bing Ji Jiu Yi Xue · Mar 2013
[The effects of mechanical ventilation with different tidal volumes on the expression of caveolin-1 in lung tissue and its related downstream signaling in rats].
To investigate the expression of caveolin-1 (cav-1) and its downstream signal under mechanical ventilation with different tidal volumes (VT) in lung tissue of rats. ⋯ Cav-1 and the activation of downstream signals in lung tissue participate in the development of the ventilator-induced lung injury.