Acta neurochirurgica. Supplement
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Acta Neurochir. Suppl. · Jan 2011
Comparative StudyComparison of nimodipine delivery routes in cerebral vasospasm after subarachnoid hemorrhage: an experimental study in rabbits.
nimodipine is the most widely preferred and administered calcium channel blocker in cerebral vasospasm prevention and treatment. There is no experimental or clinical study investigating the comparative effects of routine treatment modalities. ⋯ this is the first study to show the most effective drug delivery route in CVS after SAH. Nimodipine treatment in cerebral vasospasm is useful. This study showed that selective IA nimodipine treatment and IT nimodipine treatment must be preferred to IV and oral treatments of chronic vasospasm following SAH.
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Acta Neurochir. Suppl. · Jan 2011
The prediction of 30-day mortality and functional outcome in spontaneous intracerebral hemorrhage with secondary ventricular hemorrhage: a score comparison.
The original ICH (oICH) score was tested in different populations and showed good accuracy in the prediction of outcome and 30-day mortality after spontaneous ICH. The oICH was developed to stratify patients with all types of spontaneous intracerebral hemorrhage (SICH). Several modifications of the oICH score exist in the literature. ⋯ The best AUC for functional outcome was observed for the mICH-B score (0.823). For the mICH-A and the IVH score, an AUC of 0.811 was calculated. The scores that include the quantification of IVH or the grading of hydrocephalus show good accuracy in the prediction of 30-day mortality and functional outcome at 6 months in SICH with secondary IVH.
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This manuscript describes the development and ongoing integration of neuroArm, an image-guided MR-compatible robot. ⋯ NeuroArm successfully united the precision and accuracy of robotics with the executive decision-making capability of the surgeon.
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In recent years the quality of ultrasound (US) imaging has improved considerably. The integration of three dimensional (3D) US with neuronavigation technology has created an efficient and inexpensive tool for intra-operative imaging in neurosurgery. Our experience is based on more than 900 operations with the intra-operative 3D ultrasound equipment SonoWand® and some operations with the research equipment Custux X. ⋯ Compared to intraoperative magnetic resonance imaging (ioMRI), 3D US technology is advantageous in different ways: it is flexible and can be used in any operation theatre. There is no need for special instruments, and no need for radiologists or technicians. It adds very little extra time to the operation, and the investment-costs are considerably lower than for ioMRI.
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Acta Neurochir. Suppl. · Jan 2011
Fever increased in-hospital mortality after subarachnoid hemorrhage.
Fever is a common clinical complication in patients with subarachnoid hemorrhage (SAH), and is usually related to prognosis in early stage of diseases. In our study, we try to help improve the outcome of SAH by assessing possible risk factors for fever and investigating the influence of fever on in-hospital mortality. ⋯ Poor Hunt-Hess grade, presence of IVH and older age are independent predictors of fever in SAH. Fever is closely related to increased in-hospital mortality after SAH.