Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
[The changes in insulin sensitivity under stress and its clinical significance in the critically ill patients].
To observe the changes in blood glucose, serum insulin level and insulin resistance of critically ill patients during the acute stage and explore the relationship between the changes and their prognosis. ⋯ The study suggests that FBG and ISI could be used to evaluate the severity and prognosis. Hyperinsulinemia is found in some critically ill patients, but FINS is not helpful for assessing the severity and outcome.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
[The effect of recombinant interleukin-10/Fc fusion protein on lipopolysaccharide-induced acute lung injury in mice].
To clarify the regulatory role and mechanism of recombinant interleukin-10/Fc (rIL-10/Fc) fusion protein on inflammatory parameters during development of acute lung injury (ALI) induced by lipopolysaccharide (LPS) in a murine model. ⋯ rIL-10/Fc fusion protein inhibits release of TNF-alpha and IL-1 beta in BALF in a LPS-induced ALI murine model. rIL-10/Fc fusion protein improves survival rate in ALI mice by decreasing the release of pro-inflammatory cytokines.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
Multicenter Study[Non-conditional logistic regression analysis on risk factors of central venous catheter-related infection].
To study the correlation of indwelling central venous catheter and systemic infection, to study the causative microorganisms and factors contributing to infections, and the diagnosis and treatment of such infection. ⋯ Central venous catheterization is the major cause of bacteremia in hospital. The risk factors of infection are maintenance duration, location, and individual difference, and they are obviously correlated.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
Randomized Controlled Trial[The effect of different fluids on early fluid resuscitation in septic shock].
To study the effects of different fluids on blood pressure (BP), blood lactate clearance and mortality in patients with septic shock after early fluid resuscitation. ⋯ The rapid elevation of BP can improve blood lactate clearance in patients with septic shock receiving early fluid resuscitation. Compared with other fluids, HSH40 raises BP more quickly and needs lower total resuscitation volume to achieve the same goal.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
Randomized Controlled Trial[Effects of combination of midazolam and propofol on anterograde amnesia in critical patients].
To observe the effects of sedation with midazolam and propofol on anterograde amnesia in critical patients. ⋯ Combination of midazolam and propofol can not only ensure anterograde amnesia in critical patients, reduce drug dosage and adverse reactions, but also can help reduce the hospital expenses. This method may be a better sedation program in ICU.