Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
[The study on pro-adrenomedullin as a new biomarker in sepsis prognosis and risk stratification].
To assess the clinical value of pro-adrenomedullin (pro-ADM) in the prognosis and risk stratification in sepsis. ⋯ The measurement of pro-ADM is a new and useful marker in sepsis prognosis and risk stratification.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
Comparative Study[The impact of quality of cardiopulmonary resuscitation on post-resuscitation inflammatory reaction in a porcine cardiac arrest model].
To evaluate the effects of quality of non-standard cardiopulmonary resuscitation (N-CPR) and new guidelines recommended standard CPR (S-CPR) on post-resuscitation inflammatory reaction in a cardiac arrest (CA) porcine model. ⋯ High quality CPR not only improves survival of CA pigs, but also alleviates post-resuscitation inflammatory reaction.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
[The different effects of glutamine on macrophage cytokines release in vivo and in vitro].
To evaluate the effects of glutamine (Gln) on macrophages cytokines release and heat shock protein 72 (HSP72) expression in vivo and in vitro, and explore the anti-inflammation mechanisms of Gln during sepsis. ⋯ Gln can promote inflammatory cytokines release from macrophages in vitro, which cannot be attenuated by HSP72 expression induced by Gln in LPS challenged RAW264.7 macrophages. Gln treatment significantly decreases intracellular TNF-alpha and IL-6 levels in vivo during sepsis. HSP72 expression increases after Gln treatment both in vivo and in vitro. These data implicate that HSP72 may not play a major role in attenuating the inflammatory response after Gln administration in sepsis.