Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2009
Review Meta Analysis[Evaluation of efficacy of thymosin alpha1 in the treatment of sepsis: a systematic review].
To assess the effects of thymosin alpha1 to enhance immunity and on the prognosis of sepsis. ⋯ The current evidence shows that thymosin alpha1 improves the immuno-suppression and helps recovery of the patient from disease. However not enough evidence is found in decreasing the mortality. Further randomized controlled trials should include the dosage, duration of the treatment and timing of using thymosin alpha1.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2009
[The vicissitude of pathogenic bacteria isolated from critically ill patients in an intensive care unit during a period of using antibiotics].
To observe the changing spectrum of the pathogenic bacteria during seven-day antibiotics targeted therapy in an intensive care unit (ICU). ⋯ New antibiotic resistant pathogenic bacteria appears after seven-day antibiotic-targeted therapy in ICU. The change of species of pathogenic bacteria is related to the duration and type of using antibiotic, and also the age and length of stay. The longer time of use and the more different types of antibiotic used, the older in age and the longer in length of stay, the change in species of pathogenic bacteria is more predominant. Monitoring the dynamic change of pathogenic bacteria, adjusting the antibiotic promptly and rational use of antibiotics are very important to decrease the change in species and antibiotic resistance of the bacteria.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2009
[Study of the role of endoplasmic reticulum stress mediated apoptosis signal pathway in sepsis-induced splenic lymphocyte apoptosis].
To investigate the role of endoplasmic reticulum (ER) stress-mediated apoptosis signal pathway in extensive apoptosis of splenic lymphocytes in sepsis. ⋯ These results demonstrates activation of the ER stress response in lymphocytes and that ER stress may contribute to abnormal lymphocyte apoptosis during sepsis.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2009
[Evaluation of compliance with bundle treatment in the management of severe infection].
To evaluate compliance with bundle treatment in the management of severe infection in a tertiary hospital, aiming at analyzing clinical data in order to popularize guidelines for management of severe sepsis and septic shock. ⋯ Bundle treatment for severe infection is complied with partially in our hospital, suggesting that it is still quite arduous to popularize guidelines for management of severe sepsis and septic shock in our country.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2009
[Characteristics and treatment of multiple organ dysfunction syndrome in patients with trauma in the Wenchuan earthquake on 12th May, 2008].
To analyze the characteristics and treatment of the multiple organ dysfunction syndrome (MODS) in patients in the Wenchuan earthquake on 12th May, 2008, in order to provide theoretical reference for future care for such patients. ⋯ Fracture of bones of extremities are predominant injury in the earthquake related diseases, and the cause of death is closely associated with multiple trauma and ARF, systemic infection of large wound surfaces. The central nervous system, respiratory system, circulatory system, renal function, circulatory system should be monitored during the treatment. Adequate preparedness is essential in order to cope with the peak period of occurrence of serious complications after a disaster.