Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2011
Multicenter Study Comparative Study[CCERW: a new rule to predict treatment failure in patients with community-acquired pneumonia in middle aged and elderly people].
To develop and validate a clinical rule to predict treatment failure in middle-aged and elderly patients suffering from community-acquired pneumonia (CAP) in China, and to compare it with other prognostic rules. ⋯ CCERW can help physicians to distinguish high and low risk leading to treatment failure in middle-aged and elder patients with CAP, and has better predictable capability than PSI, CURB65 and CRB65. We prudent recommend the simple rule can be used in the middle-aged and elder patients with CAP of Han race people in China.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2011
Meta Analysis[The influence of high positive end-expiratory pressure ventilation combined with low tidal volume on prognosis of patients with acute lung injury/acute respiratory distress syndrome: a Meta-analysis].
To compare the effects of high and low positive end-expiratory pressure (PEEP) levels on prognosis of patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). ⋯ As compared with conventional ventilation, high PEEP and low tidal volume ventilation are associated with improved survival and a lower rate of barotrauma in patients with ALI/ARDS. It is necessary to further confirm the role of high PEEP only in the ventilation strategy in patients with ALI/ARDS.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2011
[Effect of bone marrow mesenchymal stem cells engraftment on secretion of inflammatory cytokine in the early stages of smoke inhalation injury in rabbits].
To explore the effect of bone marrow mesenchymal stem cells (MSCs) engraftment on secretion of tumor necrosis factor-α (TNF-α), interleukins (IL-1β, IL-6, IL-10) in peripheral blood and lung homogenates in the early stages of smoke inhalation injury. ⋯ MSCs engraftment could decrease pro-inflammatory cytokines and increase anti-inflammatory cytokines in the early stages of smoke inhalation injury, thus ameliorates inflammatory response, which confers protective effect on smoke inhalation injury.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2011
Randomized Controlled Trial[Effects of high positive end-expiratory pressure combined with recruitment maneuvers in patients with acute respiratory distress syndrome].
To investigate the clinical effects and safety degree of high positive end-expiratory pressure (PEEP) combined with lung recruitment maneuver (RM) in patients with acute respiratory distress syndrome (ARDS). ⋯ High level PEEP combined with RM can improve gas exchange and oxygenation, decrease ventilator associated lung injury (VALI). RM was safe and had good tolerance, no hypoxemia, barotrauma and hemodynamic instability were observed.