Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Oct 2011
Randomized Controlled Trial[Platelet parameters and platelet Toll-like receptor 4 (TLR4) expression in patients with sepsis, and the effect of a joint treatment-plan integrating traditional Chinese and western medicine: a clinical study].
To examine the efficacy of a treatment regimen combining modern (Western) medication and a traditional Chinese medicinal recipe Modified Liang-Ge San on sepsis, and its effect on platelet parameters/activation, platelet TLR4 expression and the intensity of inflammatory response in the patients. ⋯ In patients with sepsis, platelet TLR4 expression is elevated together with platelet activation. The joint application of Western medicine and Modified Liang-Ge San may suppress such up-regulation in TLR4/other inflammatory mediators, and alleviate platelet activation/thrombocytopenia in these patients.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2011
Randomized Controlled Trial Comparative Study[Comparison of sedative effect of dexmedetomidine and midazolam for post-operative patients undergoing mechanical ventilation in surgical intensive care unit].
To study sedative effect and safety of dexmedetomidine and midazolam for post-operative patients undergoing mechanical ventilation(MV) in surgical intensive care unit(SICU). ⋯ Sedative effect of dexmedetomidine is satisfactory for patients undergoing MV after operation, with the property of easier arousal, lower delirium rate, and it helps to shorten the duration of MV with reduction the dosage of fentanyl by 50%. However, it is necessary to enhance observation in order to prevent and control hypotension and bradycardia.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2011
[Combined effects of elevated body position on gastroesophageal reflux and intra-abdominal pressure in mechanical ventilated patients].
To investigate the combined effects of elevated body position on gastroesophageal reflux and intra-abdominal pressure (IAP) in patients undergoing mechanical ventilation (MV) who were receiving enteral nutrition, and to find out their proper height of head of bed. ⋯ Although elevation of the body position of MV patients can reduce gastroesophageal reflux, it also increase the IAP. When the body position is elevated to 45 degree angle, the number of reflux is not reduced effectively, while the rate of high esophageal reflux and the patients' IAP are increased significantly, indicating that 30 degree might be the proper body position for the MV patients receiving enteral nutrition.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2011
Meta Analysis[Efficacy of heat and moisture exchangers and heated humidifiers in preventing ventilator-associated pneumonia: a meta-analysis].
To demonstrate the effects of heat and moisture exchangers (HME) and heated humidifiers(HH) in preventing ventilator-associated pneumonia (VAP). ⋯ This study suggests there is not a significant reduction in the incidence of VAP in patients humidified with HMEs during MV, even in patients ventilated for 7 days or longer. This finding is limited by lack of enough RCTs and blinding. Further large sample of high quality RCTs is necessary to examine the wider applicability of HMEs and their extended use.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2011
[Clinical analysis of non-invasive positive pressure ventilation in immunocompromised host with acute respiratory failure].
To evaluate the value of non-invasive positive pressure ventilation (NPPV) in immunocompromised host (ICH) complicated by acute respiratory failure (ARF), and to investigate predictive variables of success with NPPV in ICH with ARF. ⋯ As an early treatment for ICH with pulmonary infections suffering from ARF, NPPV can be effective for the ICH patients suffering from severe pulmonary infection through improving hypoxemia, ameliorating respiratory distress symptoms, and avoiding complications associated with IMV when SAPSIIis less than 38. CD3(+), CD8(+), and the LIS can be used to evaluate the prognosis of those patients.