Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2011
[Effect of Buyang Huanwut decoction on apoptosis of splenocytes in rats with sepsis].
To observe the change in number of spleen T lymphocyte, B lymphocyte, apoptotic splenocytes and the expression of Bcl-2 and Bax protein in rats with sepsis; to study the effect of Buyang Huanwu decoction (BYHWD) on the immune function in rats with sepsis. ⋯ BYHWD improves the immunological suppression in rats with sepsis by lowering apoptosis of CD4(+) T lymphocyte and B lymphocyte in spleen, and its underlying mechanism may be that BYHWD produce a decrease of apoptosis through Bax.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2011
[The effects of fluid resuscitation with different crystalloid-colloid ratio on extravascular lung water index in severe acute pancreatitis].
To investigate the effects of fluid resuscitation with different crystalloid-colloid ratio on extravascular lung water (EVLW) in patients with severe acute pancreatitis (SAP). ⋯ In order to guide early fluid resuscitation,EVLW, ICP and BNP should be monitored and limited fluid resuscitation strategy with an increasing colloid ratio should be adopted for SAP patients.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2011
[The prognostic value of N-terminal pro-B-type natriuretic peptide in patients with severe sepsis and septic shock].
To evaluate the prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with severe sepsis and septic shock. ⋯ Plasma NT-proBNP level is a valuable prognostic factor for severe sepsis and septic shock patients.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2011
[Dynamic changes in plasma levels of urokinase type plasminogen activator and urokinase type plasminogen activator receptor in patients with systemic inflammatory response syndrome].
To study the dynamic changes in plasma levels of urokinase type plasminogen activator (uPA) and urokinase type plasminogen activator receptor (uPAR) and their influence on prognosis in patients with systemic inflammatory response syndrome (SIRS). ⋯ Coagulopathy is present in SIRS patients, the plasma levels of uPA and uPAR are high in patients with SIRS, and the increase of uPAR in patients with SIRS indicates a poor prognosis.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2011
[The effects of administration of valproic acid on organ function and outcome in a canine lethal hemorrhagic shock model].
To investigate the effects of valproic acid (histone deacetylase inhibitor) on visceral function and outcome in a canine lethal hemorrhage model. ⋯ The results indicate that intravenous injection of VPA promote MAP, increase urinary output, alleviate visceral injury and improve the survival rate at 72 hours in canines suffering from 42% blood volume loss, it might be an effective drug for hypovolemic shock, especially in war or other site of mass casualties in an austere environment.