Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · May 2011
[Expression of soluble triggering receptor expressed on myeloid cells-1 in septic patients and its relation with prognosis].
To approach the relationship between the contents of soluble form of triggering receptor expressed on myeloid cells-1 (sTREM-1) and prognosis in patients with sepsis. ⋯ The serum sTREM-1 are elevated at early stage in sepsis patients. It can reflect the severity of the condition. The sTREM-1 level, which might be considered as a potential prognostic factor for septic patients, is significantly correlated with APACHEII score.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · May 2011
Randomized Controlled Trial[Clinical study on plasma soluble triggering receptor expressed on myeloid cells-1 in patients with sepsis].
To observe the dynamic changes in plasma soluble triggering receptor expressed on myeloid cells-1 (sTREM-1), and to approach the effect on predicting outcome of the patient with sepsis combined with sepsis-related organ failure assessment (SOFA) score. ⋯ The plasma sTREM-1 concentration was elevated at the early stage in patients with sepsis. Dynamic changes in sTREM-1 level combined with SOFA score may be helpful in predicting outcome of the patient with sepsis.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · May 2011
Meta Analysis[Granulocyte-monocyte colony-stimulating factor for the treatment of sepsis: a meta analysis].
To systematically assess the effects and safety of granulocyte-monocyte colony-stimulating factor (GM-CSF) in the treatment of sepsis. ⋯ The current evidence shows that, compare with the conventional therapy the GM-CSF has the benefit of improving immune function, reducing the complications of infection, and shortening the duration of mechanical ventilation. However, there is no difference in reducing mortality and adverse event, or shortening the length of stay in hospital or ICU and SOFA score with the use of GM-CSF.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · May 2011
[The relationship of ultrastructure and function of hypothalamus-pituitary-adrenal axis in early stage of sepsis in rats].
To observe the changes in ultrastructure and function of hypothalamic-pituitary-adrenal axis (HPAA), and to approach the relationship between them in early stage of sepsis in rats. ⋯ In septic rats, the HPAA was excessively activated, and ACTH and CORT in plasma, and CRH in hypothalamus were significantly increased in early stage of sepsis. The changes in ultrastructure of HPAA were obvious, and the change in function was closely related to the ultrastructural changes.