Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
Comparative Study[Prediction of outcome of elderly patients with respiratory failure: comparison of current scoring systems].
To evaluate the predictive power of current scoring systems applied in elderly patients with respiratory failure. ⋯ All the four current scoring systems , i.e. APACHE II, APACHE III, SAPSII and Marshall score, presented satisfactory predictive power in prognosis of elderly patients with respiratory failure.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
Controlled Clinical Trial[Study of the effects of mechanical ventilation on the heart function of patients with echocardiography].
To study the effects of different positive end expiratory pressure (PEEP) levels on the heart function of patients undergoing mechanical ventilation (MV) with echocardiography. ⋯ Under the same condition of MV, change in PEEP levels (0-14 cm H(2)O) do not produce any obvious effect in the normal cardiac function group, on the other hand when PEEP≥10 cm H(2)O left heart function is significantly lowered in the poor cardiac function group. Optimal PEEP may improve the cardiac function.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
[Experimental study on acute respiratory distress syndrome and analysis of relevant factors in rabbits subjected to thoracic blast trauma].
To reproduce acute respiratory distress syndrome (ARDS) model in rabbit induced by chest blast injury and to analyze the pathogenesis and causes of early death in order to provide the basis for the early diagnosis of lung blast injury and its early warning system to facilitate an early treatment. ⋯ In an airtight environment, rabbit ARDS model can be reproduced successfully by blast injury with 1 917.3 mm Hg explosion pressure; TNF-α and IL-6 are involved in the pathogenesis and development of ARDS in blast injury. Pneumothorax as a result of lung rupture is the chief reason for early death and dysfunction of circulatory system is also an important reason in producing early death.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
Randomized Controlled Trial Comparative Study[A comparison of bispectral index and sedation agitation scale in guiding sedation therapy: a randomized controlled study in patients undergoing short term mechanical ventilation].
To compare the value of bispectral index (BIS) monitoring and sedation agitation scale (SAS) in guiding intensive care unit (ICU) sedation therapy for the patients undergoing short term mechanical ventilation. ⋯ BIS monitoring is better in sedative control than SAS assessment for ICU patients undergoing short term mechanical ventilation.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
[Effect of inhalation of aerosolized unfractioned heparin on peri alveolar coagulability and inflammatory response in endotoxin induced acute lung injury rat model].
To observe the local changes in alveoli in intravenous endotoxin induced acute lung injury (ALI) rat model after inhalation of aerosolized unfractioned heparin (UFH), and to observe its effects on coagulability, fibrinolysis and inflammatory response. ⋯ It was proved that inhalation of aerosolized UFH resulted in lowering local coagulability, alleviating fibrinolytic depression, improving fibrinolysis , and attenuating inflammation in endotoxin induced ALI rat model. More prominent results will be obtained when it was use as a prophylactic measure. The optimal time of usage is 6 hours after endotoxin injection.