Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Oct 2008
[Effects of ventilation in prone position combined with recruitment maneuver on lung injury in dogs with acute respiratory distress syndrome].
To evaluate protective effect and its mechanism of prone position ventilation (PPV) combined with recruitment maneuver (RM) as a lung protective ventilation strategy on oleic acid-induced acute respiratory distress syndrome (ARDS) in dogs. ⋯ Protective ventilation strategy combined with RM is safer in prone position than supine position, and it alleviates lung injury in dog with ARDS.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
Randomized Controlled Trial Comparative Study[A comparison of efficacy and safety in the treatment of hyperglycemia with continuous subcutaneous insulin with insulin pump or multiple insulin injections daily in critical elderly patients].
To compare efficacy and safety in the treatment of hyperglycemia with continuous subcutaneous insulin infusion (CSII) or multiple daily insulin injection (MDI) in critical elderly patients. ⋯ CSII can better control blood glucose and alleviate inflammatory response and improve prognosis in elderly critically ill patients.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
Randomized Controlled Trial[The study of the mechanism of the effect of heparin on tissue perfusion of sepsis patients].
To assess the role of heparin administration in the early stage of sepsis and its mechanism of action. ⋯ The use of heparin at the earlier period of sepsis can inhibit the lowering of PLT and increase of D-dimer and lactic acid significantly, prevent microvascular thrombosis, improve the tissue perfusion, and decrease active bleeding.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
[The potential role of high mobility group box 1 protein in immune dysfunction and its regulatory mechanism after major trauma].
To investigate the potential effect of high mobility group box 1 protein (HMGB1) on host immune response and its molecular regulation mechanism as well as its interventional pathway following major burns/trauma. ⋯ These data proved that HMGB1 not only acts as a novel "late" inflammatory mediator but is also closely associated with immunosuppression after acute insults. HMGB1 might play an important role in inducing systemic inflammatory response together with host immunological dissonance, resulting in the development of septic complications. Intervention of HMGB1 expression and release presumably provides a potentially effective way to regulate both excessive inflammatory and immune response, thereby as a measure to improve the prognosis of severe sepsis secondary to major trauma.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
[The impact of sepsis bundles on mortality in patients with sepsis shock: a prospective clinical study].
To survey the impact of sepsis bundle on prognosis of septic shock. ⋯ Sepsis bundle is able to improve survival rate in patients in septic shock. Compliance with sepsis bundles is low before training, and training can improve the compliance and decrease mortality rate of septic shock.