Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Oct 2008
[The role of disequilibrium of expression of matrix metalloproteinase-2/9 and their tissue inhibitors in pathogenesis of hyperoxia-induced acute lung injury in mice].
To investigate the role of matrix metalloproteinase-2/9 (MMP-2/9) and their tissue inhibitors (TIMP-1/2) in pathogenesis of acute lung injury (ALI) induced by hyperoxia. ⋯ Hyperoxia causes ALI in mice, and disturbance of MMP-2/TIMP-2 balance plays an important role in the development of hyperoxia-induced ALI in mice.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
Randomized Controlled Trial[The study of the mechanism of the effect of heparin on tissue perfusion of sepsis patients].
To assess the role of heparin administration in the early stage of sepsis and its mechanism of action. ⋯ The use of heparin at the earlier period of sepsis can inhibit the lowering of PLT and increase of D-dimer and lactic acid significantly, prevent microvascular thrombosis, improve the tissue perfusion, and decrease active bleeding.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
Randomized Controlled Trial Comparative Study[A comparison of efficacy and safety in the treatment of hyperglycemia with continuous subcutaneous insulin with insulin pump or multiple insulin injections daily in critical elderly patients].
To compare efficacy and safety in the treatment of hyperglycemia with continuous subcutaneous insulin infusion (CSII) or multiple daily insulin injection (MDI) in critical elderly patients. ⋯ CSII can better control blood glucose and alleviate inflammatory response and improve prognosis in elderly critically ill patients.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
[The impact of sepsis bundles on mortality in patients with sepsis shock: a prospective clinical study].
To survey the impact of sepsis bundle on prognosis of septic shock. ⋯ Sepsis bundle is able to improve survival rate in patients in septic shock. Compliance with sepsis bundles is low before training, and training can improve the compliance and decrease mortality rate of septic shock.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
Comparative Study[A comparison between serum myoglobin and acute physiology and chronic health evaluation II score in the evaluation of disease severity and prognosis in critically ill patients].
To determine the clinical significance of serum myoglobin (Mb) in the evaluation of severity and prognosis of non-cardiogenic critically ill patients by comparing with acute physiology and chronic health evaluation II (APACHE II) score. ⋯ Compares with APACHE II score for evaluation of critical illness, Mb can also be considered as a significant biomarker to evaluate the seriousness of the ailment in the critically ill and to judge the effect of the treatment.Therefore, it could be used as a prospective and meaningful biomarker for a quick evaluation of the disease severity in the ICU, so it is worth for further study.