Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
Comparative Study[A comparison between serum myoglobin and acute physiology and chronic health evaluation II score in the evaluation of disease severity and prognosis in critically ill patients].
To determine the clinical significance of serum myoglobin (Mb) in the evaluation of severity and prognosis of non-cardiogenic critically ill patients by comparing with acute physiology and chronic health evaluation II (APACHE II) score. ⋯ Compares with APACHE II score for evaluation of critical illness, Mb can also be considered as a significant biomarker to evaluate the seriousness of the ailment in the critically ill and to judge the effect of the treatment.Therefore, it could be used as a prospective and meaningful biomarker for a quick evaluation of the disease severity in the ICU, so it is worth for further study.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
[Role of transduce molecules and modulatory factors of signal pathways of Toll-like receptor in inflammatory response of children with sepsis].
To investigate the role of transduce molecules and modulatory factors of signal pathways of Toll-like receptors (TLRs) in aberrant inflammatory response in children with sepsis. ⋯ Aberrant expression of signal pathway molecules and the modulators in TLRs signaling might play an important role on production and development of abnormal inflammatory response in children with sepsis.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Sep 2008
[Effect of treatment with anti-receptor for advanced glycation end products antibody on multiple organ dysfunction and mortality in rats after severe thermal injury].
To observe the effect of treatment with anti-receptor for advanced glycation end products (RAGE) antibody on multiple organ dysfunction and mortality in rats after severe burn injury, and investigate the mechanisms underlying its protective effect. ⋯ Anti-RAGE antibody could obviously improve the survival in rats with burn injury with delayed resuscitation, and it seems to be able to prevent the development of multiple organ dysfunction secondary to severe burns.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
Multicenter Study[Non-conditional logistic regression analysis on risk factors of central venous catheter-related infection].
To study the correlation of indwelling central venous catheter and systemic infection, to study the causative microorganisms and factors contributing to infections, and the diagnosis and treatment of such infection. ⋯ Central venous catheterization is the major cause of bacteremia in hospital. The risk factors of infection are maintenance duration, location, and individual difference, and they are obviously correlated.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2008
[The changes in insulin sensitivity under stress and its clinical significance in the critically ill patients].
To observe the changes in blood glucose, serum insulin level and insulin resistance of critically ill patients during the acute stage and explore the relationship between the changes and their prognosis. ⋯ The study suggests that FBG and ISI could be used to evaluate the severity and prognosis. Hyperinsulinemia is found in some critically ill patients, but FINS is not helpful for assessing the severity and outcome.