Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · May 2008
[Change in coagulation after open abdominal wound subjected to seawater immersion].
To explore the effects of hyperosmotic fluid and low temperature on hemorrhage and coagulation system after immersion of dogs with open abdominal wounds in seawater. ⋯ Obvious vascular endothelial cell dysfunction, platelet activation, inhibition of coagulation factor activity, coagulopathy, and disorders in thrombosis and fibrinolysis system activation occur after dogs with open abdominal wounds are immersed in seawater.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2008
[Protective effect of intralipid on myocardial ischemia/reperfusion injury in isolated rat heart].
To investigate whether intralipid could protect perfused hearts of rats against ischemia/reperfusion (I/R) injury when it was administered before (preconditioning) or after the adverse ischemic event (postconditioning), in order to ascertain if intralipid would be a novel therapeutic strategy for myocardial I/R injury. ⋯ Intralipid administered before or after ischemia can decrease the level of CK, LDH and IS during reperfusion in isolated rat hearts. Intralipid postconditioning improves mechanical function.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2008
Randomized Controlled Trial[Midazolam attenuates mental stress in conscious patients during cardiopulmonary resuscitation performed next bed in intensive care unit].
To evaluate the mental stress level and alterations in circulatory physiology in conscious patients during cardiopulmonary resuscitation (CPR) performed next bed in intensive care unit (ICU), and to investigate the possible effective interventions. ⋯ Mental stress is significantly heightened in conscious patients during CPR performed next bed in ICU, and it induces severe circulatory physiological alterations. Psychological nursing alone is not affective in alleviating this acute mental stress. However, low dose of midazolam is found to be an effective intervention.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Mar 2008
Practice Guideline[Guidelines for resuscitation of hypovolemic shock (2007)].
Hypovolemic shock is a pathophysiologic condition produced by rapid and significant loss of intravascular volume, leading sequentially to hemodynamic instability, decreases in oxygen delivery, decreased tissue perfusion, cellular hypoxia, cellular and organ damage, multiple organ dysfunction syndrome(MODS) and may end in death. Early recognition of hypovolemic shock and prompt systematic intervention will help avoid poor outcomes. The guideline is aimed to review the clinical aspects of hypovolemic shock (including definition, pathophysiology, monitoring, diagnosis, therapy, endpoints of resuscitation, et al.) and provide recommendations according to evidence.